Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16121 Barasertib-hqpa GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 56 VGLL4; NFATC3; ZNF586; HBP1; PCGF3; BCL10; NAB2; ZNF331; RXRA; MXI1; ZNF665; RBFOX2; NR1D2; ACTL6B; ID3; CTBP1; ZFPM2; CUX2; CBX7; JUP; NR4A3; ZFHX4; TWIST1; KLF13; CBFA2T3; ZNF91; ZIC1; BCL11A; FOXN3; NR4A2; ID1; ZNF423; ZFP36L1; ZNF711; SNAI2; TRIM29; VPS72; ATF3; IRF8; ZBTB20; PAX5; PLAGL1; PBX3; TOB1; MECOM; ID4; SOX17; MEIS2; INSM1; SPDEF; KLF9; TRIB3; CRYM; ARNT2; CREB1; FOS
Down-regulation 28 CCNA2; TRIM28; HOXC6; ELF1; HOXC10; ZMYM2; BMI1; CITED1; FLNA; ZMIZ2; RBPMS; SAP30; CRY1; ARNTL; CD3D; SPEN; BATF3; NKX3-1; SAP18; SFPQ; JARID2; AFF1; PIR; BHLHE41; PITX1; MYB; PBX1; STAT5B