Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16120 Barasertib-hqpa GSE70138 MCF10A Human 24h 0.37uM EID0005
Types Number Response transcription factors
Up-regulation 36 MEF2C; ZNF274; GTF2I; ERG; WWC1; MTF2; HDAC9; SOX9; TCF4; NRBF2; TP63; EGR2; NPAS2; RUNX1; IRF7; CBX6; SMAD3; BTG1; NKX3-1; KLF4; THAP11; ID2; BNC2; FOSB; EDF1; BCL3; NFE2L3; AHR; BHLHE41; MAF; DACH1; TFAP2C; ZNF512B; MNDA; SOX11; FOS
Down-regulation 22 CREG1; THAP4; HMGB2; MSX1; HOXC10; HTATIP2; HMGB1; HOXB2; CD3D; TGIF1; IRF1; PDLIM1; SALL1; SIX2; AEBP1; TXNIP; OSR2; HOXB7; MEOX2; HOXB6; LEF1; EMX2