Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16119 Barasertib-hqpa GSE70138 MCF10A Human 24h 1.11uM EID0005
Types Number Response transcription factors
Up-regulation 47 PAX8; MEF2C; CEBPD; ZNF665; TXNIP; DEAF1; BACH1; BCL6; JUN; CARHSP1; FLI1; NR2F1; FOSB; KLF4; WWC1; NR1H3; BASP1; HIPK3; MAF; RNF14; ZBED2; ZBTB38; GTF2IRD1; TFEC; BHLHE41; ERBB4; MECOM; SALL1; SATB1; AHR; FOXC1; TRIM22; DLX5; DACH1; ZEB2; ZFP36L1; TRIM29; EMX2; SOX9; JUP; ELK3; ATF3; MNDA; EGR2; WT1; TSC22D1; KDM5D
Down-regulation 32 MAFG; TGFB1I1; ZNF281; CARM1; TBL1X; ZNF580; PIAS1; RUNX3; ZNF551; STAT6; BATF; MYB; CNOT3; NR5A2; IRX5; PIAS3; FOXL2; COPS2; KLF10; DDIT3; TWIST1; ZBTB16; GATA6; ATF5; INSM1; OSR2; INSR; CALR; EHF; ARID4B; MEOX2; MEIS2