Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16118 Barasertib-hqpa GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 89 KDM5A; EP300; FOXO4; NFAT5; PNRC1; ZNF532; ID4; BBX; ETV7; TSG101; ELF2; ELF4; PKNOX2; TP63; CREB3L2; PLAG1; TCF15; KAT2B; BTG1; CBX7; NCOA2; AR; BARX1; TBL1X; SP100; NR0B1; ZNF667; LIN28A; MYOG; MEOX1; RXRA; ZBTB20; ZNF500; PBX1; GRHL2; SOX13; HBP1; LDB1; TRIM29; SPIB; RCOR1; JUP; TRPS1; HES1; ZNF345; NANOG; SP110; BASP1; OLIG2; SNAI2; TBX3; MAF; CERS4; SOX2; DLX5; IRF7; TCF4; ZHX2; TCF7L2; BHLHE40; HMGB3; FOXG1; BCL11A; TOB1; RSF1; CUX2; ZBTB16; PLAGL1; WT1; ARID4B; MYCL; ID1; ELF5; NKX2-2; SOX9; NR1D2; BACH2; HEY1; TGIF1; ESR1; ATF3; TRIM22; PEG3; MAFB; MNDA; ZFPM2; KDM5D; ARNT2; FOS
Down-regulation 28 TRIM28; GTF2I; PSMC3IP; PHOX2B; CBX3; RUVBL2; MLXIP; REPIN1; EPAS1; HOXC6; RNF138; HMG20B; RBM14; GATA6; HIPK3; BCLAF1; COPS2; CEBPG; TAF10; POU4F1; HOXB7; CNOT3; LEF1; STAT5B; IRX5; ELK3; ZIC1; CREB1