Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16117 Barasertib-hqpa GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 43 E2F2; KLF1; TFEC; ZNF148; RNF141; TXNIP; TSC22D3; PRDM1; HSBP1; TAL1; SMARCA2; ZBTB38; HOXB5; SMAD3; PITX2; LPIN2; TCF21; BHLHE40; SOX11; ZFP36L2; TBL1XR1; KAT2B; ZNF22; NR1D2; ZBTB16; IRF1; SAP30; TRPS1; ST18; HOXB2; TRIM22; ZEB2; EGR3; TSC22D1; MYB; HOXB6; TGIF1; PBX3; TOX; SATB1; CREB1; CRYM; LEF1
Down-regulation 32 RUNX3; NR2F6; HIRA; SMARCD2; SHOX2; DLX2; NFKB1; TWIST1; CHD7; TSC22D2; CTNNB1; MYBL2; PCGF2; HEY1; INSR; FLNA; HNRNPD; HHEX; CITED2; MECOM; FOS; IRF8; IRF4; FOSB; ESR1; ZNF512B; ID4; OSR2; MEIS2; TFAP2C; EMX2; ID1