Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16115 Vemurafenib GSE70138 MCF10A Human 24h 0.12uM EID0005
Types Number Response transcription factors
Up-regulation 29 ZBTB38; FOXO3; TULP4; WWC1; SMARCA2; RBBP4; EYA2; FOXC1; BASP1; CREB3L2; TRIM16; AHR; SPEN; SUB1; NR1D2; MEIS1; BHLHE40; TRIM29; SOX9; NR2F1; HLTF; LITAF; BCL3; CITED1; SATB1; WT1; PEG3; ZBTB18; TSC22D1
Down-regulation 44 MDM4; TAF1A; ZNF3; SALL2; ZNF140; MED21; ZNF43; CCDC59; SOX11; ZNF32; SMAD1; BACH1; ZNF623; TRIM22; MECOM; IRF9; CCNC; STAT6; CREB1; MEOX2; ARID1A; IRF8; SMARCC2; ARNT2; E2F8; STAT1; SP140L; NCOR2; TBL1XR1; ZNF232; ZBTB20; CEBPB; ZHX2; POU2AF1; TRIB3; JUP; IFI16; ZFP36L1; BCL11B; INSR; KLF4; EGR2; NFATC4; MAFB