Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16112 Vemurafenib GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 41 PPARD; TBL1X; TSC22D3; ZNF83; SOX5; ZNF117; MEF2A; RXRA; NFE2; TFEC; BACH1; E2F3; HIVEP1; ZNF467; MNT; RUNX1; SOX3; FLNA; EMX2; HIPK3; SREBF1; MED1; ZEB2; SPEN; ID4; KLF9; DMTF1; PCGF2; ZNF512B; HOXC10; PAWR; KLF11; FLI1; EGR3; ZNF266; BHLHE40; TRIB3; AHR; GATA6; TXNIP; ZNF22
Down-regulation 21 TFDP2; YEATS4; KAT6B; TCF21; TCF4; ZNF410; SUB1; PAX5; FOSB; RUNX3; IRF6; SMAD7; IRF4; ATF3; MYB; INSM1; FOS; SNAI2; ELK3; MEIS2; SATB1