Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16111 Vemurafenib GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 69 TSC22D3; GLI2; LIN28A; HOXB2; POU5F1B; ZNF611; ZIC3; ZNF135; CBX7; SOX13; PNRC1; ATF4; SUPT3H; TCEA1; XBP1; HBP1; IRF9; BCOR; SIX3; BARX1; SMARCD3; TP53; ZNF239; ID4; ZNF217; NANOG; TCEA2; NPAS2; CREB3L2; DLX5; DLX2; PITX2; ZBTB20; TRPS1; KAT2B; BNC2; TGIF1; CREB3L1; POU2AF1; FOXF2; ELF5; PBX3; ELF3; NKX2-1; SNAI2; ZNF264; PAWR; TLE4; CUX2; FOXN3; HLF; KLF11; VPS72; ID1; PBX1; ST18; ZSCAN18; HOXD1; ID3; SSBP2; ARNT2; TRIM29; KLF9; SOX9; NR4A2; KDM5D; ZNF423; TFAP2C; BHLHE41
Down-regulation 36 ADRB2; SOX4; EGR1; CHD7; MYBL2; DEK; EED; CCDC59; CBFB; CRY1; RNF138; TSC22D2; ETS1; ZNF200; BRD2; CEBPA; KLF7; NR2F2; SFPQ; ATF5; NPM1; BHLHE40; NR3C2; MED24; SUB1; ELK3; JUNB; BCLAF1; KLF10; CD3D; PURA; YWHAB; STAT5B; ASCL1; HOXC6; CREB1