Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16108 Nu-7441 GSE70138 MCF10A Human 24h 0.37uM EID0005
Types Number Response transcription factors
Up-regulation 56 PAX8; IKZF1; MNAT1; MEOX1; EZH1; TRIM29; SIX1; ZNF93; ZNF195; MTF2; CREB3L2; TCF4; NFE2L3; ZHX2; KLF13; SALL2; JUP; SIX2; ZBED2; IL16; HOXB2; RERE; ESR1; BHLHE41; HDAC9; MYCL; MITF; TCEA1; WT1; KAT6B; TBX3; MEIS1; CEBPZ; SOX17; SALL1; ATF3; IRF4; DLX5; ZNF91; SSX1; OSR2; IRF8; CITED2; BACH2; LOXL2; LITAF; EMX2; TXNIP; SPDEF; TFAP2C; MYRF; PBX3; PBX1; FOS; MEIS2; ARNT2
Down-regulation 36 KLF10; ATF4; TEAD1; KLF2; GATA4; SMAD5; TAF9B; NR1D2; IRX5; JUNB; RUNX1; ZBTB38; HSBP1; HEY1; FLNA; EGR3; SMAD1; ZNF302; STAT3; TGFB1; POU4F1; FOXD1; CREB1; CD3D; TWIST1; HLTF; FOXF2; ID3; BCL3; TOX; ID4; ZIC1; POU2AF1; MYB; STAT5B; ID1