Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16100 Pd-0325901 GSE70138 MCF10A Human 24h 3.33uM EID0005
Types Number Response transcription factors
Up-regulation 243 TSC22D3; ADRB2; PNRC1; PBXIP1; EP300; CALCOCO1; ZMIZ1; ZNF611; TRIM29; TRIM16; ARID5B; TSHZ2; ZNF669; SRCAP; IRF9; ID2; CEBPD; MEIS1; TBX10; ZNF688; ZNF665; ZNF160; MEF2C; NR1H2; MZF1; RING1; HOXB3; ELF4; SOX4; RFX3; ATF2; PRDM2; AR; ARID5A; VGLL4; TP63; CDIP1; NR5A1; NCOA3; ALX3; NFE2L2; SALL2; ESR2; ZSCAN31; MYF5; ZNF268; HDAC5; ZNF768; JUP; HMBOX1; DYRK1B; GLI2; FOXO3; OVOL2; ZNF208; PHF8; ING4; SUPT7L; ZNF44; PDLIM1; CSDC2; ZNF224; HBP1; RARB; RARG; TBX4; GATA6; STAT2; PRDM14; MECP2; LITAF; TBX5; THRB; MKL1; TRIM22; CRX; JUND; TEAD3; YEATS2; NFE2; ZKSCAN4; RCOR3; ZFHX3; SMARCD3; SIX3; KAT2B; KLF5; ZNF133; NR0B2; TBX19; IRF6; SUPT6H; ZSCAN9; HDAC9; CREBL2; OSR2; POU5F1B; HIF3A; ZNF500; ISL1; RORC; WNT4; MAML3; REL; KDM4C; SIM1; GATA2; NCOA2; ERBB2; ZNF165; ZNF223; ZNF117; PEX14; SNAI2; ZNF362; SREBF1; ELF3; EPAS1; ZNF512B; ZNF257; HOXA3; PBX1; BNC2; AHR; ARHGAP35; CBFA2T3; JUN; MDM2; SOX5; GFI1B; TCF15; L3MBTL1; ZNF195; ZNF667; MNT; HESX1; HOXA4; ZNF593; TRIM24; ZNF652; ZHX2; FOXJ1; ATF3; TCF21; PRDM12; ZNF444; ZNF350; HEY1; ZNF264; REPIN1; TXNIP; E2F5; SOHLH2; EHF; SP110; BTG1; SPIB; ZNF43; TRPS1; ZNF345; BCL11A; SSBP3; CREB3L2; ZNF467; ZMYND8; RXRA; ZNF544; VGLL1; CUX2; TCEB2; CBX7; TCEA2; TP53; IRF7; MECOM; MEIS2; LIN28A; MYCL; SOX3; SOX17; NR0B1; PAWR; SOX13; FOSL2; PEG3; SIX2; CREB5; HOXB5; PLAGL1; DBP; BCL6; CHD3; KLF4; HMGN3; HIC2; SOX2; KLF13; NR5A2; TFEC; MITF; ZNF93; TCF7L1; SCAND1; ZNF331; MXI1; ZNF91; DLX5; RSF1; HLF; HOXD1; MYCN; NFATC4; ZNF711; ZSCAN18; IRF8; NANOG; ZFPM2; ZBTB16; MTA1; MAF; HOXB2; ERBB4; TCF4; ESR1; TLE1; ID1; PBX3; FOXO4; SSX1; CREG1; POU2AF1; ZEB2; WT1; SOX11; HOXB6; ID3; ARNT2; ZIC1; MYRF; EMX2; SSBP2; MNDA; INSM1
Down-regulation 100 CCNA2; FOSL1; HMGA2; EZH2; CDK2; FOXM1; TFDP1; PSMC3IP; BRCA1; MYBL2; MTF2; EGR1; FHL2; CENPF; HMGB2; DNMT1; GMNN; CHAF1B; YEATS4; PA2G4; WWTR1; HMGA1; DEK; TCERG1; PTTG1; NUP62; RBL1; BLM; RUVBL1; NPM1; WDHD1; PPRC1; BCLAF1; DNAJC2; NFIB; BAZ1A; UBE2I; RNF138; HLTF; MED6; SAP30; CCDC59; HNRNPD; CBX5; EGR3; TFAM; ITGB3BP; RAN; EED; WHSC1; CBFB; ELK3; ING3; TRIM28; PSMC3; BRD7; NPAT; HMGB1; RBM14; SUB1; ETS1; CRY1; SUV39H1; SMARCA5; TTF1; BATF3; ETV4; SSRP1; SFPQ; CHD7; HSF2; ZNF200; SMARCE1; ARID4B; SIM2; ETV5; ECD; CARHSP1; HOXC6; CCNE1; HOXC10; AGO2; ING2; XBP1; BMI1; CEBPZ; YWHAB; MED1; PURA; CBX3; HOXB7; MSX1; SATB2; ZEB1; NR2F1; NR2F2; LEF1; EGR2; CREB1; FOS