Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16099 Pd-0325901 GSE70138 MCF10A Human 24h 10uM EID0005
Types Number Response transcription factors
Up-regulation 495 TSC22D3; PAX8; ZNF688; HBP1; ZNF536; PNRC1; CBX7; PRDM2; CDIP1; GLI2; MEF2C; THRB; HLX; ZNF671; SOX17; CIITA; RFX1; OSR2; CUX1; CALCOCO1; SOX4; SOX2; ZSCAN9; CSDC2; TLX2; ZSCAN31; ZNF268; ZNF423; ZNF165; NR5A1; BNC2; SP4; SUPT7L; RFX3; ZBTB48; ZNF510; ZNF816; NEUROG3; AFF2; GATA3; TULP2; SETDB1; ZNF304; TRAK1; MEIS1; HIF3A; VENTX; ASCL3; MYF5; POU6F1; MAPK8IP1; ZNF221; ZNF529; TBL1Y; ZNF287; GATA2; ZNF506; PRDM9; ING4; MAK; CBFA2T3; ZBTB7C; ZFP2; NR1H2; IRF9; ZIC4; YEATS2; MAML3; EMX1; ZNF606; TBX6; TRIM29; ZNF177; SOX18; TBX4; NFKBIA; CREBL2; ZNF225; WNT4; ETV2; OVOL1; ZNF112; MKL1; ZNF136; ZNF814; ZNF350; SIX5; EP300; ZNF223; TEF; HINFP; ZIC1; ZKSCAN8; BRDT; ZNF257; KAT6B; ZNF471; MLLT1; ZFPM2; ZNF507; HIC1; NFIX; HNF4G; ZKSCAN7; ZSCAN2; ELF3; ESR2; TFDP2; SIX3; FOXE3; MDM4; ZFHX3; ZNF222; DOT1L; ALX3; TSHZ2; DYRK1B; ZKSCAN4; KDM5A; SCAI; ZBTB44; GSC2; GRIP1; NRL; LMCD1; ZNF133; TP73; ESRRB; ZNF391; ZBTB3; FOXE1; SSX7; IKZF3; ONECUT1; PBXIP1; PRDM16; GLI1; ZXDB; TAF6L; LHX3; VAX2; LZTR1; IRF6; ARID5A; CHD2; ZNF155; KDM4C; ERBB4; SOX14; ZNF43; ALX4; NR0B2; ZNF556; L3MBTL1; SOX1; CREB5; JUP; CRX; FHL5; CERS4; ZNF780B; NFE2L2; ZNF835; ZNF41; ARID5B; ZNF34; ZNF442; POU1F1; ZNF208; ST18; ETV3; ZNF682; RING1; SCRT1; GCM2; LHX1; RBPJL; ZNF345; HEY1; ZNF573; CDX4; TAF4B; PAX4; POU6F2; CBX2; ZNF254; SHOX; TONSL; SOX3; BARX1; TCF4; EHMT1; IRF5; MZF1; ZNF674; ZNF749; LBX1; HOXD12; GBX1; FOXO3; E2F2; FOXD3; ZNF154; ZNF571; ZNF549; AEBP1; ZNF132; ZFHX2; PAX3; GON4L; POU4F3; TFEC; MSX2; HNF4A; ZNF701; POU3F3; ZNF264; ZNF175; ZNF33B; JUN; ZHX3; MYCL; ZNF157; SOX13; ZNF81; EMX2; ZNF250; TULP1; PRDM12; ZNF80; ZNF75D; ZNF446; PLAG1; THAP9; GBX2; HOXB3; ZNF343; SHOX2; MYT1; ZNF492; ACTL6B; ZNF124; ZNF214; FOXN1; NCOA2; ZNF224; ZHX2; GRHL2; ZNF467; TCF15; HDAC4; MECOM; MEIS2; REPIN1; PCGF3; SALL2; FOXJ1; PHOX2B; ZNF695; ASCL2; TRIM16; HNF1A; ZNF85; TEAD3; ZNF667; NR5A2; ZNF135; SRCAP; ZNF3; VHL; ZNF234; THRA; TBX19; CARF; MYRF; ZNF331; DMRT1; NHLH2; ZNF195; ZNF407; HAND2; DLX6; SNAPC4; SRY; ZNF770; ZIC3; ZNF500; JAK2; HSF4; FOXN2; HOXB8; PEG3; ZFP37; EZH1; ZNF623; LIN28A; BACH2; TCF7L1; ZNF665; SOX5; SMARCA1; HESX1; PRDM10; PAX9; SKI; KLF8; KLF11; ZNF426; ATOH1; HMBOX1; LDB1; ZBTB17; EPAS1; ESRRG; ZNF362; CEBPE; MXI1; NHLH1; ZNF248; SIM1; DLX5; ZNF235; FOXN3; ZNF219; NEUROG2; PKNOX2; PAX1; PKNOX1; IKZF1; THAP7; PAX6; ZNF675; SOX12; NEUROD1; TBX1; PROP1; HOXD3; GATA6; ZFY; POU2F3; WT1; HEY2; HOXB1; ZNF440; HOXA3; ZNF415; MXD4; IRF1; WWC1; CIR1; BCL6; ZNF74; ZNF117; HDAC5; HDAC9; FEZF2; NR1H4; AIP; VGLL1; TP63; EVX1; NFKB2; NEUROD2; SALL1; CAMTA1; MEOX2; MED25; TCEA2; ZNF44; EBF2; HOXC5; CREB3L2; ZFP30; BRWD1; TCF7L2; MGA; ZNF141; SOX21; SSBP3; FOSB; ZNF93; SIX6; NEUROG1; RXRG; EN2; ARHGAP35; MITF; BHLHE41; APBB1; BCL11A; POU2F2; ZNF140; ZNF205; GATA1; TCF21; ZNF239; TULP3; ZNF580; MYOG; ZNF334; NFATC1; PIAS4; ATF3; MNX1; STAT4; BACH1; HOXD1; ZNF444; SOHLH2; ZFP36L2; ZNF217; PRDM1; MEF2D; ZNF646; ELF4; BTG1; HIC2; POU2AF1; ANKRD1; HIVEP1; PLAGL1; NFAT5; KAT2B; MEOX1; BAZ2B; KLF13; BANP; ISL1; TRIM22; FOSL2; ZNF10; ZNF32; RARG; INSR; RORA; ZNF512B; DBP; MLLT10; SKIL; MED15; ZNF354A; ESR1; TXNIP; E2F5; TBX21; MYT1L; ZNF91; ZFP36L1; TLE2; FOXO1; TAL1; SMAD6; HIPK1; MYCN; AHR; KLF4; RSF1; FOXL2; TBX2; HHEX; ZNF12; INSM1; PGR; HLF; ELF5; ID4; SOX10; ID3; FOXA1; ZNF711; NFATC4; ZSCAN18; ZBED2; SOX11; MNDA; PBX3; ARNT2; ZNF232; CRYM; TGIF1; MAF; ARID4B; NR1D2; NANOG; PIR; LOXL2; IRF8; FOS; TFAP2C; TLE4; SNAI2; NFATC3; SSBP2; MAFB; FOXO4
Down-regulation 130 CCNA2; FOSL1; EZH2; MYCBP; RHOA; DRAP1; TFDP1; PSMC3IP; BMI1; HDAC2; HMGB2; RBBP4; NUP62; HMGA1; ENO1; ATF1; ITGB3BP; CBFB; MYC; DEK; CENPF; BRCA1; RAN; PTTG1; DNAJC2; RNF4; PARP1; UBE2I; SMAD3; BLM; HMGB1; WHSC1; TAF9; MTF2; TRIM28; HNRNPD; FOXM1; NPM1; RUVBL1; HMGB3; MLX; BCLAF1; GMNN; CBX5; TAF9B; IRX5; RFC1; ZNF143; RUVBL2; C1D; PSMC3; MYBL2; SNW1; YWHAB; SMARCE1; DR1; PA2G4; ASH2L; MED6; MNAT1; RBM14; TRIP6; RBL1; SAP30; HOXA1; CDK2; HSBP1; SFPQ; YEATS4; HOXC10; MAZ; ING2; EGR3; CCDC59; PMF1; XBP1; PSIP1; SSRP1; TFAM; SUV39H1; CCNC; DNAJC1; CTR9; FLNA; ZNF146; GATAD2A; STAT3; SUB1; TGFB1; BAZ1A; ETS1; CHD1; BCL11B; CRY1; KLF10; BHLHE40; MED21; RBM39; BATF3; ZNF281; MEF2A; RLF; EDF1; PQBP1; TOB1; NR2F2; SPEN; REST; MAGED1; TBL1XR1; NRIP1; LPIN2; ILF2; FOXJ3; HOXB7; CEBPZ; RUNX3; HOXC6; ETS2; ELK3; MSX1; FOXD1; SATB2; TRIB3; MYBL1; MYB; NR2F1; PPARG; BASP1; TCFL5