Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16092 Geldanamycin GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 207 PNRC1; NR3C1; TSC22D3; CALCOCO1; PBXIP1; HBP1; IRF9; GATA3; NCOA3; HOXA5; HOXD1; PHF1; MED12; ZKSCAN4; ZMIZ1; MECP2; ZNF219; ZSCAN31; HOXD3; ZNF467; HDAC5; ZNF688; ATF3; HOXA4; TRIM22; ID4; NR5A1; BPTF; HNF4A; ZNF33B; EZH1; HMBOX1; MLXIPL; TULP1; CREBL2; EPAS1; CEBPA; JUND; ERBB4; ZNF500; TBX10; HOXB3; ELF4; CBFA2T2; ERBB2; SIX3; BRD4; DYRK1B; CIR1; CDIP1; TP73; RXRG; NCOA2; RING1; HNF4G; MZF1; ZNF91; SIRT2; ZNF589; SIX6; SPI1; MYF5; PRPF6; HMX1; IRF6; TCF25; DBP; SALL2; PRDM12; HEY1; MXI1; LYL1; JUP; MNT; STAT2; HSF4; GFI1B; TP63; ING4; PBX1; ZMYND8; SUPT7L; CBX7; HOXA3; ZFHX3; TEAD3; MEOX1; MXD4; ZNF93; ZNF117; BANP; NFE2L1; SMAD6; ZNF345; RORC; ATOH1; PDLIM1; VGLL1; BCL6; SOX3; TRIM29; ZNF224; TSHZ2; THRA; ZNF611; SMARCD3; WNT4; KLF5; SOX18; ZNF331; LITAF; ZNF44; MEIS2; ZNF536; TLE2; SPEN; PFDN5; PAX6; EP300; HSF1; ZKSCAN1; TCF15; HOXB1; BAZ2B; HOXB5; NR1H2; ARID4B; ZNF165; BRD8; TP53; ZSCAN18; BTG1; BARX1; TCEA2; DDIT3; NFATC1; OVOL2; SREBF1; IRF7; HEY2; TRPS1; FOXO4; PHIP; ZNF350; TFDP2; SMARCA1; TFAP2C; TULP3; ZNF580; AR; FOXA1; HDAC9; TCF7; SP140L; CHD9; ZHX2; GRHL2; TDP2; ZNF268; BHLHE41; TCF7L2; TFEC; RARG; HOXB2; SP100; ZNF544; NR4A1; EYA1; KLF13; NR5A2; FOXC1; HIC2; FOXF2; INSR; SIX2; SOX13; NFE2; NPAS2; VPS72; NR4A2; MAF; TCEA1; KDM5B; NR0B1; ST18; ZNF423; ARID5B; TOX; ARNT2; TOB1; SOX17; HMGN3; GATA6; TXNIP; PIR; RXRA; TBX3; OSR2; MYRF; TRIB3; SSBP2; BCL11A; NR2F6; NFATC4; HOXB6; PBX3; ID3
Down-regulation 108 CCNA2; ADRB2; MYC; RUVBL1; HMGA2; EZH2; PPRC1; MYBL2; FOSL1; SUV39H1; FHL2; PARP1; DRAP1; HMGB1; SMARCA4; TCERG1; NUP62; TBP; MYCBP; TAF1A; PSMC3IP; EED; NPM1; DNAJC2; DDX54; BAZ1B; NFIL3; WDHD1; EGR1; XBP1; RBM14; ZBTB24; CCDC59; SUB1; PA2G4; ELK3; RBL1; HNRNPD; RAN; BLM; BAZ1A; NFKB1; WDR77; TERF2; CBFB; ING3; ZNF107; PREB; HSF2; TFAM; SMAD5; C1QBP; TAF1D; ZNF267; HOXA10; EDF1; NFX1; PLAGL2; ECD; RUVBL2; ZBTB18; EGR3; BATF3; TFDP1; GATAD2A; TSC22D2; CEBPZ; UBP1; TRIM32; BMI1; ZNF146; ENO1; BRCA1; LEF1; ITGB3BP; HES1; ETS2; SSRP1; YWHAB; NELFB; SMAD1; BCLAF1; ING2; RBPMS; ARNTL2; GTF3A; ZNF22; SAP30; FOXD1; CHD7; BIRC2; HLTF; SATB2; PIAS3; ZBTB38; ZFP36L2; MED1; JARID2; MYB; PTRF; IKBKAP; ETV1; BASP1; SOX11; EGR2; NR2F2; KDM5D; HOXC6