Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16091 Geldanamycin GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 327 PNRC1; NR3C1; NCOA3; CALCOCO1; TOX3; BTG1; ZKSCAN4; PBX1; SPI1; TSC22D3; BAZ2A; HBP1; ZNF467; ZNF362; RSF1; MED12; ZNF224; IRF9; ZNF688; TRIM22; NR5A1; ERBB4; LITAF; PBXIP1; ZNF331; ZNF611; ZNF91; HIF3A; ZNF500; RXRB; KAT8; HOXA5; NR4A2; MZF1; GCM1; ZKSCAN3; PHF1; MXI1; BPTF; CDIP1; SALL2; MKL2; L3MBTL1; TEAD3; SOX3; MAML3; POU2F3; DYRK1B; RING1; TRPS1; ZMIZ1; ZSCAN16; TP73; TLE2; POU3F4; SRY; EMX1; ATF3; PRDM2; TFAP2A; CEBPA; HNF4G; FOXA1; ZSCAN31; SREBF2; CRX; ZNF446; ZXDB; HOXA4; CIR1; ZNF701; DAXX; TULP2; POU3F2; ZNF667; MYF5; PRDM9; LHX6; ZBTB44; DLX4; TCF25; EPAS1; GATA3; BARX1; ZNF219; TCF7; DLX5; TBX6; ZNF160; SCAI; HEY1; ZNF778; ZNF214; ZNF135; ZNF33B; EZH1; CARF; ZNF44; FOXI1; ZSCAN9; ZBTB3; MECP2; ZNF165; CHD2; CREBL2; ZFHX3; POU1F1; ZNF80; POU6F2; ZNF623; OSR2; PRDM14; IKZF3; MEOX1; NCOA2; HOXD13; HOXB3; MEF2C; STAT2; ZNF345; ZNF665; ST18; BRD4; DLX2; PPARA; ZNF257; ZNF148; MEIS2; HEY2; ZNF536; VENTX; HSF4; HMBOX1; SMARCA1; CDYL; HDAC5; TAF7L; ZNF606; IRF6; CBFA2T2; TFEC; FEZF2; ZNF12; CHD9; ZNF223; ZNF721; MEIS1; ZNF34; ZNF415; NCOA1; HOXB2; ZNF248; ZNF136; BAZ2B; ZKSCAN1; AES; SIX3; ID4; ELF4; SMARCC2; NR1H3; MLXIPL; ZNF112; TSHZ2; DACH1; ERBB2; ARID5A; FOXJ1; KLF3; TFCP2L1; ZKSCAN8; ZNF682; ZNF225; ZIC3; WNT4; ZNF587; TGFB1I1; FOXN3; THRB; LHX3; ZMYND8; TULP3; ZNF768; HOXA3; E2F5; NR1H2; HSF1; PEX2; MDM2; CREB3; TDP2; SOX21; ZNF573; BRD2; FLI1; ZNF264; CBX7; OVOL2; CERS4; HOXD1; HIVEP2; TCF7L1; SOX2; HMGB3; TGIF2; RORC; SOX13; NR5A2; ZNF205; MED13; ZNF350; SIM1; MEF2D; ESR1; ARRB1; SOX18; NFKB2; ZNF141; TCF7L2; ARID5B; DDX17; BRWD1; PHIP; EHMT2; BCL11A; RARB; MXD4; MNDA; HOXB5; REL; THRA; TCF15; MYCL; MYOG; ZNF444; TLX3; NFATC1; ZNF711; HIC2; AR; TCEA2; JUP; SSBP2; ZNF580; ZNF117; PDLIM1; ZNF93; FOXO4; RAD21; HDGF; TXNIP; TFDP2; TFAP2C; PHF20; NAB2; STAT6; NHLH2; CUX2; KMT2A; SSBP3; TBL1X; INSR; IRF1; BCL6; GRHL2; KLF11; INSM1; ZNF304; RYBP; NR4A1; BASP1; ING4; DBP; TRIM29; ARID4B; SOX17; ZNF512B; PAX6; ARID1A; MAF; NEUROD1; TULP4; KLF13; ZBTB20; KAT2B; ZNF652; ZSCAN18; KLF5; VPS72; TRIB3; HDAC9; NKX2-2; ARNT2; FOXO1; KDM5B; WT1; TCF4; RBM39; ZNF423; TP63; CREB3L1; CBFA2T3; TBX3; NFATC4; CRYM; WWP1; PEG3; TGIF1; FOXA2; DDIT3; EYA1; MEOX2; SPDEF; ZNF281; ATF1; RXRA; TAL1; FOS; MECOM; TOB1; ZIC1; TWIST1; HOXB6; GATA6; ZHX2; EMX2; CREB1
Down-regulation 126 CCNA2; ADRB2; MYC; TCERG1; HMGA2; EZH2; PARP1; SMARCA4; FHL2; PPRC1; RUVBL1; DRAP1; FOSL1; MYCBP; RBM14; BAZ1B; MYBL2; SUV39H1; ABL1; GTF2A2; NUP62; PSMC3IP; C1QBP; NPM1; DDX54; NOC2L; HMGB1; SUB1; MYBBP1A; MLX; RUVBL2; DR1; WHSC1; NFKBIA; TBP; CHAF1B; RBL1; HLTF; BRPF1; TFAM; NFIL3; CBFB; XBP1; FOXD1; FOXM1; CRY1; POLR3F; PA2G4; GATAD2A; WDR77; BATF3; PTTG1; YEATS4; HSF2; ARNTL2; DNAJC2; ELK1; ZBTB24; RAN; ELK3; ETV4; BAZ1A; CCDC59; NELFB; HNRNPD; TTF1; WDHD1; BRCA1; RHOA; BCL10; EGR1; PREB; TRIM32; ZNF593; ETV5; CEBPZ; HES1; SMAD5; BMI1; ACTL6A; RBPMS; TRRAP; ING2; RNF141; TBPL1; BLM; SF1; ENO1; ITGB3BP; KLF6; PQBP1; ALX1; SMAD7; BCLAF1; YWHAB; IKBKAP; ZBTB18; HOXB7; NEDD8; TFDP1; MLXIP; TSC22D2; CTR9; ZFP36L2; PURA; JUNB; SSRP1; TRIM28; HLF; GTF3A; KLF2; DDX5; ID1; BIRC2; HOXC6; TRIP6; LEF1; THAP11; ID2; ETV1; EGR3; SAP30; TCFL5; PUF60; MAFB; KDM5D