Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16090 Geldanamycin GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 390 NR3C1; CALCOCO1; PNRC1; ZNF446; ZNF219; MEOX1; PBXIP1; TSC22D3; CDX1; ZKSCAN4; HBP1; HOXD3; RSF1; ZNF362; ZNF606; ZNF611; HNF4G; HIF3A; ZNF331; FOXF1; ID4; ZNF500; MZF1; HMBOX1; NCOA3; SIX3; EZH1; GATA3; ZBTB44; ZNF814; CREBL2; ZKSCAN3; ZNF44; ZNF467; ZSCAN16; ZNF688; BAZ2B; MED12; CDIP1; ZNF224; ZNF701; PBX1; TP73; ELF4; CBFA2T2; GLI2; RXRB; ZNF264; HOXA4; NR5A1; NR4A1; ZSCAN18; PPARA; ETV3; ZNF91; PHF1; RFX3; ZNF350; TBX4; ZNF778; EMX1; DYRK1B; CEBPA; ZNF345; SOX3; HOXA5; NCOA1; RXRG; TEAD3; TULP1; ZNF587; HOXD1; FOXJ1; SALL2; CRX; DLX4; NR6A1; TAF1C; ZNF444; CIR1; MAML3; ATOH1; ZFHX2; APBB1; WNT4; FOXH1; ZNF135; IRF9; HOXB2; ZNF136; HNF4A; ZNF223; CHD2; ZNF667; NHLH1; KAT6A; RING1; TRIM22; ZNF85; ZNF33B; TULP2; POU6F2; ZNF254; PRDM9; ZNF235; ZNF214; HINFP; ERBB4; PFDN5; SRY; ZNF669; ZNF12; ZNF665; CBX7; ZNF155; SIX6; VENTX; ZSCAN9; ZNF358; TBX6; MED25; KAT2B; POU2F3; ZNF550; PRDM14; HOXB3; ZNF225; HNF1A; SMARCC2; ZNF682; ZMIZ1; KDM4A; KLF5; BRD4; ZNF80; ZNF536; ONECUT1; BNC2; THRB; ERBB2; MYCN; MYF5; CIITA; IKZF3; SCAI; TXNIP; TFAP2A; ZKSCAN1; FOXJ3; CDX2; MEIS2; ATF3; MBD1; TCF25; ZNF304; ZNF117; BPTF; FLI1; GCM1; POU1F1; ZNF507; GBX2; ZNF175; MITF; TBX10; LITAF; ZNF141; SAP130; HOXA2; MXI1; ZNF93; ZNF160; HSF4; RORC; SKI; NKX3-2; NFATC1; NR1H2; PKNOX2; TCF7; ZSCAN31; ZNF671; RFX2; ARID3B; ZNF253; PITX3; ZNF816; ZNF257; TGFB1I1; ZNF154; ZNF423; BARX1; RARG; BTG1; HOXB5; NEUROG2; ZFHX3; NCOA2; TBX21; KLF15; HEY1; ZNF415; TRIM29; HOXD9; MYCL; SETDB1; HOXA3; GRHL2; CERS4; RORA; ARID5A; MED14; MEOX2; ZNF589; ZEB1; ZNF133; NR4A3; PLAGL1; ZNF112; FEZF2; ZNF432; ZNF586; KLF3; JUND; ZNF75D; HOXB13; EP300; LDB1; CSDC2; RARB; IRF6; ZNF211; NFKB2; GBX1; SIM1; RAX; ZNF132; KDM5C; SKIL; ZKSCAN8; SOX13; ZIC3; LHX3; CHD9; BCL11A; ZNF768; JUP; SOX18; NHLH2; TSHZ2; HDAC5; SOX5; STAT2; ZNF544; TFDP2; EYA1; MAF; EBF2; PRDM10; POU2F1; ELF3; SOX17; ZNF124; AFF2; KLF13; MXD3; TP63; TAL1; PRDM12; TGIF2; E2F5; HOXB1; USP21; ZNF184; PRDM2; SMAD6; FOXA1; TLE2; ZNF711; ZNF623; ING4; TBX1; ZNF248; ZBTB20; GFI1B; PEX2; TCF21; RBPJ; ZNF324; TFAP2C; MXD4; ZNF419; FOXO4; CREB3; CUX1; PDLIM1; TCEA2; THRA; ZNF134; ZNF430; DACH1; MSC; EHMT2; OSR2; KLF1; SMARCD3; TULP3; OVOL2; ZNF43; SP2; NR5A2; KLF7; EPAS1; REPIN1; BRWD1; PBX2; HDGF; ZHX2; GATA1; FOXN3; TOX; TDP2; GATA2; ARID4B; TSG101; ZNF394; MEIS1; TLE4; HLX; FOXF2; TFEC; ARID5B; CBFA2T3; NR4A2; ZNF580; TOX3; NPAS2; CREB3L2; VPS72; STAT4; MKL2; SOX2; ZNF329; HIC2; SRCAP; NFAT5; AR; CREM; ZNF551; WT1; TRPS1; TCF15; MECOM; CNOT3; FOSB; ZNF24; HOXB6; TBX3; ARID1A; FOXA2; SSBP3; MYRF; AES; ARNT2; TRIB3; PHIP; DLX5; RYBP; TSC22D1; MNDA; JUN; ISL1; ZNF217; PAX6; ST18; KDM5B; ZNF165; PIR; HMG20B; SSBP2; ID3; NFATC4; TWIST1; FOS; RXRA; CRYM; EMX2; TCF4; BHLHE41; CREB1
Down-regulation 125 CCNA2; MYC; ADRB2; HMGA2; FHL2; NFKBIA; FOSL1; EZH2; PARP1; MYBL2; PPRC1; RUVBL1; DRAP1; SUV39H1; DR1; MYCBP; PSMC3IP; NUP62; RBM14; C1QBP; GTF2A2; RAN; HSF2; CHAF1B; EDF1; BAZ1B; NFIL3; TFAM; RNF138; DNAJC2; TAF9; NPM1; TERF2; CCDC59; XBP1; HLTF; FOXM1; GABPB1; UBP1; TFDP1; EED; BAZ1A; PMS1; SMARCA5; ZNF593; SUB1; EGR1; ENO1; BATF3; BCLAF1; HMGB1; CBFB; TAF1A; RBL1; XRCC6; MLX; PA2G4; GATAD2A; PPARG; ELK1; BLM; GCFC2; PRKDC; CTNNB1; SMARCE1; TAF1D; ZBTB24; MED24; UBE2I; ZNF107; BMI1; DNMT3B; SFPQ; BRD3; NELFB; RBPMS; HMGB2; ING2; HOXA10; HNRNPD; TSC22D2; BRCA1; CEBPZ; SAP30; SSRP1; POLR2A; MED1; CTR9; ZBTB18; HOXC6; HLF; CITED2; PQBP1; TBPL1; RBBP4; ZNF146; TEAD4; YBX1; SERTAD2; PTRF; BIRC2; RUVBL2; JUNB; HES1; NRBF2; CRY1; SF1; SNAI2; PTTG1; HOXC10; ELK3; MAFF; HMGA1; ID2; IRX5; MAGED1; FLNA; PITX1; YWHAB; MAFB; NFIB; SMARCA2; TRIP6; NR2F2; EGR3