Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16089 Geldanamycin GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 318 PNRC1; NR3C1; CALCOCO1; HBP1; NCOA3; ZKSCAN4; ZNF688; TSC22D3; PBXIP1; ZNF467; ZNF79; HOXA4; NR5A1; GATA3; BARX1; SALL2; CIR1; ATF3; HOXD3; TP73; PHF1; ZNF667; JUP; TLE2; ID4; RSF1; TCF25; TBX6; ZMIZ1; KAT6A; ZNF506; NCOA2; ZNF446; MED12; HOXB3; TEAD3; GLI2; HOXA5; MED14; CBX7; ERBB4; HDAC5; EMX1; ZNF500; SOX3; PBX1; ZNF345; ZNF350; MEF2C; ARHGAP35; TFAP2C; ZNF331; APBB1; ZNF254; ZNF33B; HIF3A; HNF4G; HINFP; HIC2; BCL11A; ZFHX3; TBX5; CERS4; ELF4; DLX4; ZNF135; TP53; SUPT7L; FOXH1; ALX3; ZBTB44; ZSCAN31; L3MBTL1; HOXA6; BAZ2A; IRF9; ZSCAN18; EZH1; NR4A2; ZNF432; ERBB2; CRX; ZNF665; CREBL2; HOXD1; HEYL; ZNF611; POU2F3; HMBOX1; MED25; ZBTB3; ZNF292; REL; HESX1; IRF6; ZNF112; ZNF44; WNT4; GLI1; TSHZ2; ATF2; THRB; KAT2B; CEBPA; TOX3; TRIP11; ZSCAN16; ZNF117; ZNF224; ELF3; RORA; PPARA; TBX1; TRIM29; ZNF606; HOXB5; CDIP1; PFDN5; OSR2; NKX3-2; RNF111; SOX12; SPI1; MYF5; RXRB; ARRB1; DYRK1B; TBX3; ATOH1; ZNF536; TBX10; ZNF91; POU6F2; ZNF768; BNC2; NR1H3; LZTR1; OVOL2; BPTF; PRDM14; RING1; MZF1; ZNF175; SRY; CEBPD; AFF2; AR; ZNF257; ZNF93; ZNF225; GRHL2; TFAP2A; BRD4; ZNF589; PAX8; NR4A1; SOX18; ZNF682; THRA; BCL6; PRDM2; ZNF155; CSDC2; CNOT2; ING4; EPAS1; ZNF74; ZNF248; TCF7L2; ZNF132; PIAS4; ZNF444; ZNF304; ZNF160; TCF15; BTG1; CIITA; FOXO4; LITAF; ZNF12; TRIM22; ZNF141; MEIS2; ZNF223; JAK2; PKNOX2; HIVEP2; TCEA2; SUPT3H; SETDB1; NFATC1; SMARCD3; LDB1; ZNF226; CEBPZ; INSR; ZNF154; HDAC9; SMARCC2; ZNF415; TRAK1; MXD4; SOX2; RORC; MEOX1; ZBTB20; TFEC; CHD9; PLAG1; BAZ2B; EVX1; TRPS1; ZIC3; TSG101; NAB2; ZNF85; KDM5C; EP300; MYCL; ZNF423; RBPJ; TCF7; LHX3; HSF1; DAXX; TFDP2; PDLIM1; ZNF544; CDYL; KLF5; RFXANK; THAP7; MED23; FOXI1; ZNF711; WT1; TULP3; SOX13; NR3C2; HOXB13; RARG; NR1H2; BRWD1; MKL2; ZEB1; KLF13; FLI1; RARB; AES; FOXF1; ZNF671; PHIP; ST18; ZNF394; HOXB1; ZNF623; TGFB1I1; TGIF2; SIX3; ZMYND8; SHOX2; NPAS2; KLF3; ZNF268; HOXB2; ZNF580; MDM2; ZNF217; FOXA1; FOXA2; BHLHE41; SMAD6; ZNF165; ARID4B; PIR; PIAS1; TCF21; CUX2; ZNF195; FOXF2; E2F8; CNOT3; SSBP3; NR5A2; ZFPM2; EYA1; WWP1; ZHX2; SATB1; ESR1; TBL1X; TRIM16; DDIT3; AEBP1; NFATC4; MXI1; THAP10; ARNT2; HIRA; GATA6; ARID5B; SOX17; MED13; TWIST1; TP63; TRIB3; HOXB6; HEY1; SSBP2; ASCL1; TOB1; PEG3; TLE4; TCF4; PBX3; NR2F6; CRYM; NFATC3
Down-regulation 118 CCNA2; ADRB2; MYC; FHL2; MYBL2; EZH2; RUVBL1; PARP1; FOSL1; MYCBP; PPRC1; HMGA2; BAZ1B; NUP62; SUV39H1; SMARCA4; TCERG1; CBFB; NPM1; RNF138; DRAP1; TBP; RBM14; SMARCE1; HNRNPD; MLX; YBX1; BAZ1A; RAN; C1QBP; PSMC3IP; MYBBP1A; HLTF; ZNF146; CREG1; DDX54; EGR1; GABPB1; RBL1; SMARCA5; DR1; TFDP1; NFKB1; RUVBL2; ELK3; XBP1; ENO1; ZFP36L2; PA2G4; CRY1; DNAJC2; RHOA; BMI1; FOXD1; KLF2; TERF2; PURA; IFI16; BCLAF1; HMGB1; BRCA1; MLXIP; ETS2; RBBP4; MTDH; FOXG1; ING2; PREB; RB1; SMAD5; TRIM32; HES1; MED1; HOXA10; HOXC6; CENPF; TRIP6; TSC22D2; PTTG1; TBPL1; ZBTB18; BIRC2; ARNTL2; MBD2; SUB1; CHD7; GTF3A; SSRP1; YWHAB; KLF10; JARID2; SNAI2; DNMT3B; ZBTB38; MSX1; SATB2; STAT3; ZFP36L1; ID2; JUNB; CNBP; TRIM28; ZNF22; SAP30; SMAD1; IKBKAP; PITX1; BASP1; TCFL5; MAFB; NR2F2; ZEB2; ID1; CDK2; NR2F1; PUF60; ETV1; KDM5D