Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16086 Radicicol GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 80 FOXO4; ASCL1; TSC22D4; ETV7; AFF4; NR1H2; SIRT2; CRTC1; MLXIPL; NR0B2; NR4A3; SPI1; MYOG; SOHLH2; HMX1; CDX2; SAFB; ARID3B; IRF5; NR1D2; IKZF1; DACH1; PTTG1; ZEB2; TFE3; MEF2D; PIAS2; ZNF646; MAFB; RARA; NR4A1; WWC1; TP53; AIP; CAPN15; EVX1; BLM; DNAJC1; ALX1; KLF2; NCOR2; TULP4; CNOT1; MXI1; SOX10; TCF15; ID4; FOXC1; ELF3; KLF9; TSG101; BBX; TRIM22; DDIT3; SATB1; EYA1; PBXIP1; TXNIP; RBBP7; TGIF1; TAF10; FLI1; BCL11B; TWIST1; ENO1; LOXL2; AFF1; MNDA; CHD7; AHR; SSX1; RXRA; PPARGC1A; NR4A2; HMGN3; HOXC6; SOX9; EGR3; GATA6; BHLHE41
Down-regulation 77 TTF2; EDF1; ZBED1; ERCC3; ZNF12; BTG1; SUMO1; SIM2; RBBP5; ZEB1; OSR2; ZFP36L2; MED1; E2F8; ATF7IP; GTF2I; TCF4; ETS2; ZFHX3; MYB; BRIP1; ARID4B; ZNF593; EMX2; TEAD4; CHD9; ZNF692; CREB3L1; RUNX3; NR5A2; ZKSCAN1; E2F5; ZBTB16; ARNTL2; TCF21; VDR; ZFP36L1; ZNF281; SHOX2; ZNF22; NEUROD1; CBX6; ZNF551; TSC22D1; TRIP6; TRIB3; HEY1; SOX2; CITED2; IRF9; SMAD1; SPIB; EHF; KLF11; BACH2; WT1; PAX5; ZBTB18; MEIS2; CUX1; PEG3; MEIS1; SPDEF; MECOM; ARNT2; ARID5B; AEBP1; SOX11; ESR1; ZHX2; CREB1; BASP1; TFAP2C; ID3; SNAI2; GATA2; E2F2