Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16085 Radicicol GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 61 SOX2; NCOA3; TSC22D3; TRIM22; YEATS2; FOXJ3; TRIM29; TP53; NFE2L1; FOXO1; ATF3; ZNF93; IFI16; ZMYM2; ZMIZ1; TBL1XR1; PBXIP1; TCEA2; PIR; MAF; CREBL2; TP63; BCL3; ID2; IRF6; IRF9; VDR; ZNF140; SOX13; STAT3; TBL1X; WNT4; NPAS2; PBX1; HOXB2; MEOX2; HOXD1; ZNF544; RFX5; TLE4; ARID4B; AEBP1; AHR; BCL6; TCF4; MYCL; ID4; GATA6; BACH2; ZSCAN18; KLF5; IRF4; TWIST1; WT1; HMGN3; BCL11A; ID3; JUP; MEIS2; EMX2; ZHX2
Down-regulation 58 TCERG1; CCNA2; ABL1; NPM1; TFAM; MXD1; MAML1; EGR1; HMGB1; ZNF22; HMGA2; TEAD1; PREB; RNF141; NEUROD1; NRIP1; PAX6; PTTG1; TXNIP; SMAD5; PSIP1; DNAJC2; URI1; RNF4; ST18; NR1D2; FOSL1; HMGB2; ZNF32; KAT6B; SATB2; RREB1; RERE; SFPQ; CITED1; TGFB1; SUB1; HMGA1; SUV39H1; HSBP1; BMI1; HNRNPD; MSX1; ETS2; POU2AF1; HHEX; NR2F1; SAP30; IRX5; NKX2-2; FOXF1; EGR3; ZBTB38; ZBTB18; AFF1; TRIP6; SATB1; KDM5D