Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16084 Radicicol GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 110 TSC22D3; NR3C1; PNRC1; TRIM22; CEBPD; TP53; CALCOCO1; ELF3; NAB1; BPTF; TBX2; NFE2L1; STAT6; BTG1; IRF9; MKL1; ID4; PDLIM1; BAZ2B; PBXIP1; TRIM29; ERBB2; ZSCAN31; ZMYM2; MITF; ID1; ID3; HOXA5; TCF25; ZNF224; RSF1; AHR; SMARCC2; ATF3; ZMIZ1; EPAS1; ZNF611; HBP1; BCL3; GATA3; MXI1; TCF7; TXNIP; ID2; HOXD1; NFATC1; SP100; PBX1; ZNF430; ELF4; KLF5; REPIN1; TSG101; FOSB; FOXC1; BRD8; LITAF; ZKSCAN1; PHIP; SUMO1; CHD8; NKX2-1; CHD9; BCL6; ZNF394; REL; CUX1; ZNF580; SP110; ZNF12; CREBL2; FOXF1; WNT4; SATB1; SPEN; ZNF544; KDM5B; NR4A2; JUP; ZNF512B; NCOA4; TGIF1; FOXF2; ZNF83; NCOR2; TRIM16; TFDP2; KLF10; MED13; ELF1; ARID4B; SPIB; TCEA2; HEY1; SOX13; HOXB2; ZSCAN18; TOX; MEIS1; TBX3; KLF9; ZBED2; ASCL1; TOB1; FLNA; FOXO4; BASP1; GATA6; TFAP2C; ZNF91
Down-regulation 72 CCNA2; MYBL2; HMGA2; FOXM1; EZH2; GMNN; FOSL1; RUVBL1; ADRB2; ZNF267; PSMC3IP; TFAM; HMGB2; RBL1; SUV39H1; EED; DNMT1; WDHD1; TEAD4; GABPB1; TAF1A; HMGB1; BLM; YEATS4; XRCC6; PLAGL2; CRY1; BATF3; BMI1; RNF138; ZFHX4; ACTL6A; CARM1; CCDC59; E2F6; ZBTB18; PA2G4; CAMTA1; EGR1; E2F3; ITGB3BP; NUP62; XBP1; SUB1; ETV5; EGR3; ARNTL2; CCNE1; NFIB; GTF3A; NFE2L3; SAP30; TSC22D2; BRCA1; ZNF22; ELK3; HNRNPD; MAFB; FOXA2; ZFP36L2; CHD7; NKX3-1; ETV1; TWIST1; LEF1; AEBP1; KLF2; MYT1L; IRF4; SOX11; EGR2; CDK2