Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16082 Radicicol GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 168 NR3C1; PNRC1; CALCOCO1; ZSCAN31; PBXIP1; TRIM22; SREBF2; TSC22D3; ZNF446; ZNF274; BBX; PBX1; ERBB2; CIR1; FOXO4; ZNF384; PHF1; HBP1; RXRB; KAT8; LYL1; ZNF226; ZNF219; BTG1; GATA3; HOXA5; HIF3A; RBPJ; BPTF; NCOA2; CREBL2; NFE2L1; BAZ2B; ZMYND8; SP140; ZNF688; KDM4A; MED25; TAF7; WNT4; NR5A1; DYRK1B; ZSCAN16; LDB1; RSF1; AES; MLXIPL; KMT2A; ZNF467; TSHZ2; RARB; MEOX1; HMX1; KAT6A; SREBF1; EYA1; NR3C2; CEBPA; HMBOX1; MZF1; TCF15; BAZ2A; TXNIP; ZNF224; ZNF646; ATF7IP; ZNF345; TCF25; TCF7; DLX4; ZBTB44; TCF12; SP110; ZNF117; SOX3; ZMIZ1; ZFY; SIM1; ZNF33B; ZNF85; NR0B1; LITAF; ING4; ARID4B; NFKB2; EZH1; TRIM16; MYOG; ZNF444; TEAD3; TFDP2; PRMT2; ZNF91; HTATIP2; IRF7; NR1H2; SOX10; MXD4; HEY1; IRF9; TRPS1; TRIM29; ZNF44; FLI1; BRD4; KDM5D; TFAP2C; TFEC; MITF; EP300; BARX1; ZNF606; RORA; SMAD6; JUND; ZNF350; ELF4; ZNF160; BCL11A; ATF3; TSG101; STAT6; CUX1; MED23; ZKSCAN1; JUP; GLI2; IRF6; SATB1; HOXB13; DDIT3; GRHL2; INSR; SP100; KLF5; ID4; PHF20; SP140L; TLE4; ZNF544; MEOX2; POU2AF1; ELF5; ZSCAN18; KDM5B; MXI1; TCEA2; IFI16; NR4A1; TULP3; NFE2; DACH1; ERBB4; REPIN1; PIR; MAF; FOXA1; ARID5B; BASP1; ZHX2; TOB1; MEIS2; HMG20B; OSR2; MECOM; TWIST1; HOXB2; CREB1
Down-regulation 121 CCNA2; MYC; ADRB2; RUVBL1; MYBL2; SUV39H1; NFKBIA; FOXM1; HMGA2; FOSL1; PPRC1; EZH2; GMNN; PRKDC; DNMT1; NOC2L; HMGB1; PSMC3IP; WHSC1; ZNF473; NUP62; RBL1; HMGB2; TFAM; ZBTB24; WDHD1; NFIL3; EGR1; HES1; CHD7; BLM; HSF2; DRAP1; TAF4B; PA2G4; TAF1A; NPM1; PMS1; TEAD4; CEBPD; C1QBP; CBFB; NFKB1; SUB1; YEATS4; TFDP1; BRCA1; ZNF22; RNF4; RUVBL2; HNRNPD; BAZ1B; TRRAP; TAF9B; PTTG1; GCFC2; RNF138; AGO2; SSRP1; HLF; GATAD2A; ZNF200; ZBED4; BAZ1A; RBM14; XRCC6; PQBP1; EGR3; GTF3A; ZFP36L2; NRIP1; PREB; PAXBP1; CTNNB1; CENPF; ZNF593; MAFB; AHR; PSIP1; APEX1; RBBP8; SNAI2; JARID2; ENO1; NELFB; NEUROD1; HLTF; BMI1; ILF2; SATB2; ZBTB18; HMGB3; SF1; ZFP36L1; SAP30; MAFF; CEBPZ; CDK2; KLF9; ZBTB16; THAP11; CALR; ELK3; YWHAB; TCEA1; NR2F1; RELB; BRIP1; TSC22D2; EGR2; IRF4; TCFL5; ZFPM2; MSX1; HMGN3; LEF1; SOX9; ZBTB38; TGFB1; ID1; ETV1