Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16079 Withaferin-a GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 54 TBX2; MXD1; HEY2; NR1H2; GFI1; HOXA10; CTBP1; ASH2L; AHR; CBX6; PIR; IRF5; NFE2L1; TFEB; TFDP2; IRF2; AGO2; NCOA4; HOXB7; CBX7; NFIC; ESRRG; BRD4; ZKSCAN7; HLX; TDP2; TFEC; HEY1; TCF7; KLF10; BASP1; DBP; VDR; NR1D2; ZFP36L2; BAZ1A; ZBTB38; RUNX3; KLF5; DACH1; TSC22D2; KLF9; RREB1; PAX5; ZEB2; KAT6B; MEIS1; KLF4; NR2F2; EMX2; MAFB; FOS; ID1; EGR3
Down-regulation 48 WHSC1; URI1; ZNF160; NR0B1; PRPF6; ERG; TCF12; BNC2; ATF5; BACH2; TOX3; YBX3; HLF; HOXB13; ZNF43; RORA; CREB5; ZBTB16; PITX2; SOX11; ZNF85; ZNF551; ZBTB20; TULP3; MEIS2; TCF4; HHEX; MKL2; IFI16; NKX2-2; ARID1A; HMGB2; KLF2; JUN; THAP11; SMARCA1; ZEB1; SMAD1; OLIG2; TCF7L2; ISL1; ZNF91; SNAI2; PBX3; ARID5B; CREB1; SATB1; KDM5D