Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16078 Withaferin-a GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 44 MNAT1; SIX1; ZNF274; HMGB3; TAF9B; PPRC1; POU2AF1; AGO2; BATF3; ETV1; KLF6; RBPMS; LIMD1; DDIT3; HTATIP2; E2F3; MLXIP; DNAJC1; HMGA1; KLF10; MTDH; PIR; NCOA2; LITAF; BBX; SMARCA2; SATB1; CREB3L1; HOXC10; NR1H3; ELF5; FOXC1; TRIM29; PBX1; TBL1X; MYBL1; IRX5; PBX3; NR2F2; TOX; NFIB; ZBED2; ELF1; TRPS1
Down-regulation 68 CDK8; PRDM12; GTF3A; PNRC1; HIRA; DLX5; HBP1; TERF2; ZFP36L1; FOXO1; HOXB7; ZNF468; CERS4; ZNF224; CARHSP1; PRDM2; ZNF302; EMX2; ACTL6A; ZNF12; MYRF; SOX17; FOXN3; ZNF304; PHOX2B; PRRX1; TCF4; TAL1; ARNTL2; JUNB; SUMO1; PITX2; MXI1; REPIN1; HOXB13; HOXB5; ZBTB18; BCL11B; CNBP; SMAD1; HOXB6; ZNF24; SMARCA1; MYB; HIPK1; ZEB1; AR; ID2; HIC2; HOXD1; ST18; MEOX2; MSX1; IRF8; JUN; THAP11; BCL11A; PAX6; MEIS2; CREB1; TLE4; ZNF423; EHF; SOX11; HEY1; GATA2; NFATC4; ZNF586