Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16077 Withaferin-a GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 243 MYBL1; NCOA3; SPI1; NR5A1; ZNF362; FOXO4; CALCOCO1; EMX1; ZXDB; NEUROG3; DAXX; NR1H4; SOX3; ZBTB3; ATF3; MAML3; TP73; TRIP11; KAT2B; POU3F4; ZNF257; ZNF225; ZNF701; SOX18; ZNF467; HOXB3; CIR1; ETV2; CBFA2T2; HESX1; ZNF354A; MLLT1; POU2F3; HIC2; TBX2; ETV4; FOXF2; GBX2; ZNF141; GCM1; ZNF81; ZKSCAN4; CHD2; WT1; PHIP; VHL; SIRT2; ZNF331; ELF4; SIX5; TCF7; ZNF254; THAP7; PKNOX2; IRF9; SRY; MYF5; TEAD3; HMX1; BRWD1; CBX7; CERS4; ZSCAN16; ZNF80; ZNF682; EN1; HINFP; E2F4; ZNF674; PRDM12; ZNF557; PNRC1; ZNF214; APBB1; ZNF75D; ZNF112; ZNF768; PAX4; TBX1; ZNF334; SCAI; TFAP2C; NANOG; TCF21; MEF2C; PHF1; ZNF492; ZNF646; HOXD13; LIN28A; DLX2; SOX12; ZNF205; ZNF223; ONECUT1; DMRT1; ZNF345; YEATS2; VENTX; PRDM10; ZNF444; HOXD11; TONSL; HOXD9; SOHLH2; ZNF350; ELK4; ZNF85; ZNF14; ZNF224; ZFHX3; ZNF135; TCF15; DYRK1B; ZNF93; LZTR1; CSDC2; GLI2; BARX1; FEZF2; ZBTB44; HOXA3; CBX4; DLX4; TDP2; ZNF235; EVX1; ST18; ELF5; LOXL2; TSHZ2; ETV5; ZNF239; NR4A1; HOXD1; MEOX1; ZNF155; MEF2D; SIM2; ZNF606; RBPJ; ZNF589; LDB1; ZNF33B; POU2AF1; ZNF571; TBX3; ZNF430; KDM5C; ZNF573; FOXA1; MXI1; ZNF226; TCF25; ZBTB20; MEIS2; MNDA; BNC2; NFKB2; RORA; ZSCAN31; TULP3; CCNH; SIM1; FOXI1; ZNF32; JUN; HLX; SMARCC2; TRIM22; ZNF43; BRD4; HOXB1; TEAD4; SOX13; ZNF117; TFEC; CBFA2T3; MSC; WNT4; ZNF512B; NR0B1; NR4A3; ING4; ZNF580; ZBTB16; MITF; ZNF415; PAWR; CREM; HBP1; TCF4; TLE4; ARID5B; MYCL; INSR; MTF2; ZNF268; SOX2; FOXF1; HHEX; BTG1; FOXE1; TRIB3; ZFPM2; IRF8; ARID1A; SMAD6; ARNT2; FOXN3; KLF4; GATA6; PLAGL1; PBX1; HEY1; HIRA; CREB3L2; THAP10; GRHL2; OSR2; ZNF91; NR4A2; PBX3; NPAS2; BCL6; NFE2L3; HOXB2; TRPS1; PIR; MYRF; TRIM29; BHLHE41; VPS72; JUP; ZNF423; MAF; ID4; OLIG2; ID3; MEIS1; PEG3; MAFB; NFATC4
Down-regulation 86 CCNA2; HDAC2; MYC; EDF1; WHSC1; RBM14; NRIP1; TFAM; NUP62; SUB1; HMGB1; EGR1; NAB1; BCLAF1; GTF2I; RHOA; RBBP4; STAT5B; PRKDC; NFKB1; CHD7; YEATS4; TRRAP; HMGA2; HSF2; HMGB2; IRX5; ING3; BMI1; CBX3; ENO1; UBP1; MED24; RBL2; C1QBP; XRCC6; HIPK3; MSX1; CBFB; STAT3; RUVBL2; NELFB; STAT6; CRY1; MYB; XBP1; TRIP6; TRIM25; NEDD8; BLM; RBBP8; ZNF22; HLTF; ASCL1; CTNNB1; CTR9; HOXA5; TFDP1; KDM5B; HNRNPD; ZBTB38; JARID2; SSRP1; MLXIP; KLF9; PDLIM1; ATF1; PTTG1; RFX5; NCOR2; DDX5; TAF10; ESR1; RBPMS; IRF4; PTRF; BHLHE40; ELK3; FLNA; SMAD7; FOSL1; EHF; ZBTB18; ZBED2; CREB1; ETV1