Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16076 Withaferin-a GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 280 NCOA3; ATF3; KDM5A; HBP1; CALCOCO1; DDIT3; RSF1; ZNF222; ARNT; NFE2L1; TSC22D3; ZNF654; BRF2; RLF; TSG101; HINFP; PLAG1; RNF111; GABPB1; TRIP11; TBP; EZH1; PBXIP1; ZNF254; FOXJ3; GLI2; ELF4; ZNF682; NCOA1; ZKSCAN3; PHF1; ZKSCAN4; KDM2A; WT1; MXI1; NCOA2; CIR1; SAP130; TXNIP; BRD4; IRF7; ZNF394; DLX2; ZNF345; SUPT5H; BBX; ZNF117; IKZF3; TFE3; ARID4A; JUND; BANP; ZNF212; EP300; ARID5A; MXD1; TAF7; SIN3B; ZNF473; HTATIP2; LDB1; TRIM33; ZNF675; ZNF76; TRIP4; ZNF500; SNIP1; ZNF257; ZSCAN16; ETV2; ZNF12; HDAC5; ZSCAN31; ZNF274; POLR3C; SREBF1; ZNF764; RBBP5; NFE2L2; ZNF34; RXRB; MAFG; RNF10; NFYC; HCFC2; ZNF208; SIRT7; ZKSCAN1; PNRC1; GCM1; DMRT1; BAZ2B; TOX3; HIVEP1; BTG1; HESX1; ZNF44; ZNF14; ZNF506; RORA; TFDP2; HMBOX1; ATF7IP; HEY2; TOX4; ZNF93; FOS; RING1; ZNF225; TDP2; NFAT5; SUPT7L; IKZF1; ZNF217; ARID4B; FOXO3; HOXD3; HOXD1; ZHX2; PHIP; ZNF214; TBX21; SOX3; POU1F1; XBP1; ZNF430; CIITA; ARID3B; ZNF354A; SSX1; PRDM1; CDC5L; ZNF136; IRF9; AFF4; PEX14; MDM4; SOX5; CREB5; LPIN2; ZNF426; ING4; JAK2; ZNF273; ZNF132; TERF1; SKIL; ZNF165; EGR1; KAT2B; NRBF2; SP140; ZNF423; FEZF2; SNW1; TCF7; ZNF3; STAT5A; MEOX1; TBX3; ZNF10; SKI; CHD2; ZNF467; RCOR3; CITED2; TMF1; SHOX2; ATF4; TSC22D4; NR4A1; ZMIZ1; ZNF419; ERBB4; TAF11; TRIM24; BRD8; ZFY; MEF2A; BACH1; ZNF267; LITAF; ZNF711; ZNF304; BARX1; SIX1; PHF20; IRF4; ZNF24; KLF13; MNT; BRWD1; ELF2; TGIF1; SIX2; UBE2B; RYBP; ZBTB43; BCOR; ZNF671; TFAP2C; ZNF195; CDYL; ZBTB11; HOXB2; TRIB3; GATA6; TULP4; TLE4; SMARCA1; SP100; ZNF350; TRIM16; ZNF43; CRY1; E2F3; PKNOX2; MAGED1; AR; FOSL2; NFATC1; BNC2; NFIC; ZNF232; PIAS1; TRIM29; NR1D2; PAWR; BATF; ZNF512B; SALL2; ZNF268; PIR; HDAC9; CREB3L2; BHLHE41; ZEB2; KLF3; ID4; MED13; SERTAD2; NFE2; LMCD1; HIRA; JUN; POU2AF1; MED23; DLX5; HHEX; KAT7; MNDA; TULP3; MYRF; TWIST1; STAT4; CREB3L1; ZNF189; FOXO1; FOXF2; ZNF91; NKX2-1; HIPK1; JUP; FOXO4; BACH2; PEG3; FOSB; BCL6; NANOG; TAL1; ZSCAN18; KLF4; KLF9; LEF1; OSR2; NKX3-1; ID2; KLF2; CRK; NFATC4
Down-regulation 122 CCNA2; MYC; RUVBL1; FOXM1; HMGA2; TCERG1; HDAC2; MYBL2; ADRB2; C1QBP; PPRC1; HOXA10; PARP1; TFDP1; HMGB1; SMARCA4; PA2G4; NPM1; ETS2; NELFB; SUV39H1; CBX5; XRCC6; NRIP1; CBFB; CENPB; PHF2; DDX54; EDF1; MED24; SOX4; NOC2L; HMGB2; MYCBP; RAN; DNMT1; CTBP1; HNRNPD; RUVBL2; WDR77; CENPF; UBE2I; PTTG1; DEK; GTF2I; BAZ1B; SMARCC1; SSRP1; RBM14; TCF20; GTF3A; MTA1; ZMYND11; CAPN15; ID1; WHSC1; PRKDC; RBBP7; ZNF532; ZBED4; CREG1; RBFOX2; ATF1; NR2F1; CARM1; BRD3; PURA; TRIM28; BAZ1A; BRCA1; SIM2; HMGB3; ELK3; BCLAF1; CBX3; TFCP2; ITGB3BP; TEAD4; TRIM32; PMS1; RBBP8; APEX1; ACTL6A; RBBP4; EZH2; HOXA11; HES1; RHOA; SMARCD2; HOXA5; ARNTL2; TLE2; SFPQ; DACH1; PSIP1; SMAD1; EYA2; CIZ1; ID3; BASP1; REPIN1; NFIB; BLM; CDK2; ZNF22; IRF8; TCFL5; ESR1; CNBP; HOXC6; PITX1; TGFB1; BMI1; THAP11; SOX11; NR2F2; FLNA; HMG20B; EMX2; SATB1; CREB1; ETV1