Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16075 Withaferin-a GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 83 ATF3; IRF7; FOS; EGR1; NR4A1; NCOA3; JUND; ARID5A; XBP1; THAP7; CBX4; GABPB1; JUNB; ATF4; PPARD; ELF4; DLX2; SNAI1; TGFB1I1; MED15; SMARCB1; FOSB; DDIT3; ERF; HSF1; CALCOCO1; SP110; PHF1; ZNF532; IRF9; HBP1; FOXF2; BATF3; GLI2; HTATIP2; IRF8; PITX2; RARG; LOXL2; TRIM29; ZMIZ1; LIN28A; ID3; LMCD1; SP140L; ID2; PAWR; JUP; CREB3L1; TDP2; TCF7; KLF5; NFE2; CTBP2; BTG1; FOXL2; NANOG; NR4A2; NKX3-1; TGIF1; MYCL; GATA6; HIC2; ZHX2; DLX5; BCL6; TFAP2C; JUN; SPIB; ZNF165; ZFPM2; KLF4; TBX3; SNAI2; KDM5D; HHEX; RXRA; MEIS2; TWIST1; RELB; ID1; ZSCAN18; EGR2
Down-regulation 74 MYC; CCNA2; NFKBIA; PRKDC; TCERG1; ADRB2; HDAC2; NFIL3; KAT6A; CENPF; TAF4; IKBKAP; NR3C1; BMI1; TRRAP; HES1; HLTF; HSF2; ATF5; CHD4; TCF12; CNOT1; ASH2L; MKL2; KMT2A; SPEN; RB1; CTR9; PBRM1; ZMYND11; BCLAF1; PAXBP1; SMAD5; RUVBL2; HMGB3; RBL2; BHLHE40; ZBTB11; RNF141; ZKSCAN1; ETS2; SUB1; PURA; HIPK3; HDAC4; URI1; MED24; SSRP1; RBBP7; CEBPZ; MTDH; RNF6; HMGB1; HOXA5; NFIB; BCL11B; GTF2I; TXNIP; FUBP1; RREB1; MECOM; AHR; CHD7; NR2F1; ATF1; MYB; SMAD1; ZEB2; ZBTB38; SAP30; EMX2; ZBTB18; SATB1; TCFL5