Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16074 Mitoxantrone GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 47 NCOA3; E2F2; TRIM22; PNRC1; CDIP1; PRDM12; TBX2; CALCOCO1; AFF2; CBX7; ELF4; SOHLH2; KAT2B; BNC2; BRCA1; CERS4; ATF3; ZBTB16; SMAD3; CREBL2; TCEB2; NR1H4; SHOX2; TP63; MITF; FOXF2; TCEA2; BCL6; HOXB2; FOSL2; DLX5; DLX2; FOXO1; TBX3; TFAP2C; ESR1; MYBL1; ZFP36L1; ELF1; TSC22D1; MAFB; TRIM29; ARNT2; PBX3; LEF1; TCF4; GATA6
Down-regulation 30 SMARCA4; HDAC6; ETS1; EGR1; CENPF; CRY1; BCLAF1; BRD3; HLTF; ATF1; CHD7; HMGB1; PSIP1; NFIB; MED1; SMAD1; MYB; NR2F6; BMI1; VPS72; EGR3; TOX; MECOM; PEG3; ID4; EHF; FOSL1; DACH1; ZBTB18; ETV1