Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16073 Mitoxantrone GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 70 TRIM22; ATF3; ZNF654; IRF9; ZNF669; CDIP1; NR1I3; IRF7; CALCOCO1; PBXIP1; ZNF500; IRF6; TFAP2A; SMARCD2; DLX4; ZNF44; RORA; HLF; STAT6; MXD4; HOXB13; ZIC3; HOXD1; ZNF117; ZNF665; ZNF350; BNC2; SALL2; ARID5B; NFIC; CUX2; NR4A3; IFI16; TOX; POU2AF1; AR; ZNF195; HBP1; ZNF160; LOXL2; ING4; HOXB2; HDAC9; NCOA2; ZNF512B; MAFF; ZBTB20; FOXF2; BACH1; ZSCAN18; TP63; NANOG; SSBP3; PDLIM1; RFX5; MEOX2; BCL6; LITAF; CRYM; ZBED2; CALR; TBX3; TRIB3; BCL11A; TRIM29; SATB1; HOXB6; SPDEF; ZNF91; KDM5D
Down-regulation 81 CCNA2; HMGB2; CHD7; PURA; TBP; EDF1; FOXM1; BATF3; EZH2; PTTG1; GABPB1; ATF5; PATZ1; ING3; RBM14; NFKB1; CDK8; CNOT6; PRPF6; PBRM1; MED1; SETD2; BCLAF1; BAZ1B; HNRNPD; RNF138; NCOA1; TBPL1; SATB2; SMARCE1; CENPF; CRY1; RUVBL2; PSIP1; TMF1; MTDH; TP53; ZNF410; CBX3; SSRP1; VEZF1; XBP1; TRIM28; BRD8; GTF3A; ERG; HMGA1; HLTF; TULP4; NCOA6; FOXC1; PEG3; BRD2; EGR1; RNF6; NR1D2; CREB1; SFPQ; BMI1; ELF5; SAP30; BAZ1A; KLF2; IRX5; TSC22D2; NKX3-1; NFIB; ZBTB18; SMARCA2; MYB; ELK3; RYBP; PBX3; NR2F2; BASP1; MAFB; AFF1; ID1; ETV1; HOXC6; E2F2