Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16072	Mitoxantrone	GSE70138	MCF10A	Human	24h	0.37uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	84	TRIM22; DAXX; HOXD1; ATF3; CREBL2; CDIP1; IRF9; CALCOCO1; MED12; ELF4; SP110; ZSCAN31; LZTR1; TOX3; SP100; ZNF345; ZNF611; ZNF160; SALL2; PBXIP1; ZNF224; ZNF91; REL; CSDC2; ZNF665; CERS4; ZNF44; TAF1D; MNT; IRF6; BNC2; NKX2-1; RORA; JUP; JUN; ING4; TCEB2; CREM; ZKSCAN1; SMARCA1; ZNF623; FOSB; ZNF606; MITF; ZNF652; ZNF117; TFEC; LOXL2; ZNF512B; ZNF423; TGIF2; SNAI2; ZNF264; ERBB2; GATA6; MAF; STAT1; ZFPM2; BTG1; ZSCAN18; HOXB5; PLAGL1; BCL3; ZNF544; TBX3; MXI1; FOXF1; AR; SOX17; AHR; MEIS1; MAGED1; TP63; NR4A2; ESR1; LITAF; SCAND1; PEG3; TOX; WT1; TRIM29; PBX3; BHLHE41; NFATC4
Down-regulation	75	CCNA2; FOXM1; CENPF; MYBL2; EZH2; HMGB2; TCERG1; PARP1; HMGB1; BAZ1B; RBM14; PTTG1; BCLAF1; ZNF473; WHSC1; CCDC59; CBX5; YEATS4; ING3; SUV39H1; TAF9B; SUB1; BATF3; NPM1; HNRNPD; DEK; SMARCE1; ZNF107; SMAD1; WDHD1; PSMC3IP; NUP62; AGO2; BRCA1; RNF138; SSRP1; RUVBL2; TRIM28; SAP30; BLM; RHOA; PA2G4; HMGA1; NFYB; KMT2A; HES1; STAT5B; SFPQ; NFIB; MAFB; MED1; MYB; TBPL1; POLR2A; HLTF; CBX3; CBFB; CHD7; PURA; RBPMS; SHOX2; HOXC6; HIPK3; TFDP1; MYT1L; BMI1; PITX1; EGR1; ETV1; IRF4; NR2F2; MSX1; FOSL1; NR2F1; AFF1