Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16071 Mitoxantrone GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 209 KDM5A; NR3C1; IRF7; NFAT5; PBXIP1; MDM4; CALCOCO1; TRIM22; CDIP1; CERS4; ARNT; ARID5A; GLI2; ZNF669; HABP4; ZNF768; FHL2; ZNF345; ZNF79; MXI1; TSC22D3; TULP1; ZNF611; POU3F1; IRF6; ZKSCAN1; ATF3; MXD4; NR1I3; MNT; HBP1; BCL10; SUPT5H; BTG1; TBX5; MAFK; TBX4; SIX5; NR5A1; LDB1; PNRC1; CRX; L3MBTL1; RFX7; TSG101; ZNF212; REL; ZNF224; IRF9; SOX4; SIX6; THRAP3; ZNF688; NFE2L1; ZNF358; NFIX; HOXB3; HOXB13; TEAD1; HIF3A; ZNF205; GATA3; ZNF573; SETDB1; ETV5; MDFI; CARF; ZNF665; KMT2D; NR1H2; ZNF12; BAZ2A; ZNF506; ZNF136; SOX9; DYRK1B; JUP; RSF1; ING4; GLI1; ELF3; STAT1; NR0B2; ZBED1; TBX10; ZNF124; SP110; HDAC5; EVX1; CSDC2; KLF13; PHF1; NFATC3; STAT2; JUNB; SRCAP; ZNF257; JUN; PEX14; ZNF133; YEATS2; SIN3B; CIC; SAP18; POU2F2; ZNF415; CHD4; BARX1; MAF; FOXN3; AFF2; ZNF652; ZNF350; ZNF195; TRIM29; SMARCC2; TFEB; NAB2; NR1D2; MED15; ZBTB16; TP63; SKI; SOX5; RBL2; SIX2; TCF15; BBX; CREBL2; RORA; ZNF274; CTNNB1; ERBB4; SMAD7; ZSCAN31; ZNF44; CD3D; ZNF571; ZNF117; HDAC7; ZNF589; RUNX3; ZNF671; ZFY; MAFF; NR4A3; MED14; FOXA2; HMBOX1; PPP1R13L; ZNF394; ERBB2; ZNF512B; BATF; TCEA2; BRD4; OVOL2; SPIB; ZNF91; HOXB1; TOX3; HOXD1; GRHL2; ZNF160; ZNF83; VPS72; NCOR2; ZNF43; RFX5; SP100; SMAD5; BHLHE41; CITED1; WNT4; PDLIM1; TDP2; DBP; TCEB2; HEY1; TULP3; RUNX1; KLF5; ZNF264; NKX2-1; BCL3; HLF; ZNF423; BCL6; TOX; ZNF22; ARID1A; BCL11A; SNAI2; AR; TSC22D1; TXNIP; EGR1; TGFB1; ZNF331; BHLHE40; RELB; SOX17; PCGF2; GATA6; CRYM; TBX3; HOXB6; ID2; KDM5D
Down-regulation 101 CCNA2; MYBL2; PARP1; HMGB2; CENPF; DEK; FOXM1; TCERG1; PTTG1; NPM1; AGO2; RAN; RBM14; BCLAF1; CBX5; ARID4B; TFDP1; SUV39H1; HNRNPD; BAZ1B; PSMC3IP; RUVBL1; HMGB1; CHAF1B; TAF9B; GABPA; IRF2; CCDC59; SMARCC1; WDHD1; RUVBL2; THAP1; TAF5; CCNC; NFYB; C1QBP; MED21; BLM; IKZF5; XBP1; SFPQ; BRD7; PA2G4; TAF1A; PITX1; CEBPZ; HMGB3; PREB; ZMYND11; RAD21; SMARCE1; MTDH; BRCA1; MLXIP; CITED2; RBPMS; SSRP1; NUP62; DNMT3B; TBL1XR1; HOXC6; SUZ12; CBFB; RBFOX2; ORC2; USP22; RBM39; BATF3; ENO1; TEAD4; ZEB1; CEBPG; ATF4; YBX1; TBPL1; ID1; TRIM28; NR2F2; MTF2; CBX3; CHD7; JARID2; LEF1; ENY2; NFIB; HMGA1; ARNTL2; YWHAB; ATF1; SMAD1; SAP30; HMGN3; VEZF1; ISL1; IRX5; PIR; TRPS1; ELF1; ELK3; CREB1; BASP1