Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16070 Mitoxantrone GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 243 PPARD; EED; ZNF274; ZNF654; SPI1; ZNF667; ZNF500; POU3F1; GLI2; ZKSCAN4; SALL2; CALCOCO1; ZNF611; AFF2; ZNF362; MEOX1; ZNF160; ZSCAN18; CDIP1; PNRC1; ZNF345; NR5A1; ZNF135; PKNOX2; ZNF701; ZNF536; ZNF358; ZNF669; ZBTB44; ATF3; TRIM22; ZSCAN16; OVOL2; PBX1; MAML3; TAF1D; IKZF3; PRDM9; NEUROD1; ZNF440; ZBTB3; CBX7; PLAG1; ZNF208; CTBP1; MYF5; BCL3; HMBOX1; IRF6; SUPT5H; ZNF682; MNT; ARID5A; FEZF2; ZFP36L1; AES; LZTR1; ZSCAN9; TEAD3; SP4; CNOT2; CERS4; ZNF334; RSF1; ZNF3; GCM1; ZNF573; TDP2; PFDN5; BCL10; ELF4; ZNF350; ZNF214; L3MBTL1; PAX4; NR1I2; PBXIP1; ZMYND8; TGIF2; TFEC; TLE2; ZNF415; ZNF544; RING1; ZIC3; ZNF665; BTG1; HOXD1; ZNF467; ZNF562; RORA; ZNF423; PEX14; SOX15; REL; CREBL2; SOX5; FOXF1; ERBB4; YEATS2; E2F3; ZNF589; ZNF136; ZNF44; BNC2; PHF1; CIITA; ZNF257; THRB; CHD2; ZNF223; JUP; ZNF91; PRDM12; EP300; SP100; FOSL2; INSM1; ZNF239; HMGA1; TP63; LDB1; WNT4; SMARCC2; ZNF571; FOXF2; STAT6; ZNF721; SOX17; HDAC5; ZNF512B; ST18; ZNF426; ZNF224; ZSCAN31; ZKSCAN7; ERBB2; ZNF93; TFEB; LIN28A; GLI1; BACH2; TRIM27; E2F5; ZNF671; TOX; ZNF432; ZNF165; SP140; IRF1; NFKB2; ZBTB7A; ZNF652; TOX3; HIVEP1; BCL6; LOXL2; SOX18; CAMTA2; PEG3; TCEB2; TP53; TBX3; NHLH2; IRF7; ZNF331; ZNF304; ZFHX3; KLF13; ZNF329; DAXX; ZNF264; CUX2; ING4; NR0B1; IRF9; CREM; ZNF302; NR1H4; HEY2; CRYM; SREBF1; NR3C2; TULP3; SP110; HBP1; TCF21; NKX2-2; DDIT3; JUNB; VPS72; ZBED2; MXD4; ZIC1; LITAF; ZBTB20; MAFF; KLF5; SCAND1; TRIM29; HLF; ZNF232; SNAI2; ZNF83; BASP1; PDLIM1; SMARCA1; SRCAP; AR; ZNF195; NFIC; MEIS2; ZNF117; CUX1; SPIB; NFE2; CREB3L1; MYCL; NKX2-1; RFX5; NANOG; RELB; PLAGL1; MEIS1; ID4; TCEA2; EYA1; TCF7L1; POU2AF1; TRIB3; MAF; ARNT2; SPDEF; FOXO4; HEY1; FOS; MECOM; BHLHE41; GATA6; NFATC4; EGR2; ID1; SOX9
Down-regulation 86 CCNA2; CENPF; TCERG1; MYBL2; FOXM1; PTTG1; PARP1; RNF14; HDAC2; BCLAF1; HMGB2; NRIP1; BAZ1B; CHAF1B; TAF9B; HSF2; SMARCA4; NFIL3; MYC; WHSC1; PBRM1; HNRNPD; ENO1; RHOA; FOXD1; SUB1; BRCA1; BMI1; RBM14; SUV39H1; KAT6A; PHF2; RUVBL2; ZMYND11; RBPMS; CCNC; ECD; CBX3; HOXC6; HOXB7; ETS2; PURA; NCOA6; HLTF; RAN; ITGB3BP; TBPL1; BATF3; NFYB; ZNF443; COPS2; AFF1; BRIP1; HIPK3; MTDH; SMAD5; NUP62; TRIM28; CTR9; CHD1; SMAD1; TFDP1; PAXBP1; SFPQ; BLM; XBP1; CEBPZ; CBFB; MYB; ATF1; IRX5; MAGED1; HMGB3; CDK2; NR2F2; NFIB; ZBTB18; SAP30; ETV1; LEF1; EMX2; ELK3; MSX1; EGR3; SATB1; E2F2