Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16067 Brivanib GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 15 MEF2C; TERF2; NFE2L1; IFI16; KLF11; ELF3; MYBL1; HMGB2; TCF4; ID1; PAX5; SATB1; ID3; CREB1; ELK3
Down-regulation 40 NR4A3; ARID3B; ZNF529; INSM1; CREM; HBP1; CRY1; SALL2; LEF1; NANOG; AHR; ZNF329; SALL1; FOSL2; BNC2; TGIF1; NR2F1; TSC22D1; LITAF; ZIC1; TOX3; ERBB4; PEG3; SOX13; ATF3; RUNX3; STAT4; JARID2; FOXF1; MAGED1; AFF1; ZSCAN18; ASCL1; BHLHE41; PIR; AEBP1; HEY1; FLNA; SOX9; KDM5D