Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16051 Linsitinib GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 52 FOXO4; CEBPD; NFE2L1; PNRC1; HOXB3; MEF2D; DLX4; HDAC7; CALCOCO1; MYOG; GLI3; TCF15; TULP4; TFCP2; NCOA1; ZNF589; ARID5B; HOXB2; HIC2; RUNX1; PBXIP1; KLF10; KAT2B; ZEB1; CTBP2; KLF5; ZFP36L2; BCL3; HES1; BHLHE40; JUNB; LMCD1; WWTR1; HOXD1; TRIB3; IRF1; FOXO1; PLAGL1; SIX2; RUNX3; MYRF; BCL11A; BASP1; TCF4; WT1; EHF; ARNT2; MEIS1; MEIS2; ID1; MECOM; CREB1
Down-regulation 28 HOXA5; HMG20B; SALL1; SPEN; SATB2; ING3; JARID2; LEF1; APEX1; IRX5; NR3C2; HNRNPD; ENO1; MED1; CCNC; MAFB; ESR1; ZBTB38; EGR3; MSX1; ZEB2; PCGF2; FLNA; SATB1; ELK3; EGR2; NR2F2; BHLHE41