Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16050 Linsitinib GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 36 TSC22D3; ZIC1; TAF7; BPTF; MEIS1; ZNF468; ZBTB1; ZNF302; ZNF131; BASP1; MEIS2; RBBP4; MECOM; PLAGL1; HES1; SOX17; BAZ1A; ZNF189; TRIM16; MED1; VEZF1; BRD2; FOXC1; JUNB; BRIP1; RBPMS; TSC22D2; HIPK1; MYT1L; ELK3; CUX1; ID1; SATB1; TOX; DACH1; NR2F2
Down-regulation 59 HEY2; TXNIP; CREB5; ATF5; ZBED1; ATF3; TGIF1; JUND; RNF138; ASCL1; TCF7L2; TCEA1; ELF5; NR1I2; HMGB1; DLX5; HOXC4; TCF7L1; HOXB2; TP63; HMGB2; AR; HLX; ZFP36L1; ZFP36L2; PRRX1; PTTG1; SSRP1; NR5A2; CREB3L2; HOXB6; CCNC; HOXC10; RORA; FOXO1; RYBP; MSX1; EHF; NKX2-1; TFEC; VPS72; HIC2; HMGB3; NR2F6; HTATIP2; BACH1; KLF5; CITED1; PAX5; IRF6; STAT4; KLF4; MYCL; OLIG2; ID4; HOXC6; EGR3; EGR2; NFATC4