Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16049 Linsitinib GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 40 SUV39H1; TSC22D3; CEBPD; ELF4; PQBP1; EMX2; ZNF536; HTATIP2; OSR2; STAT6; AHR; NCOA4; FOSB; PHF20; CTBP2; ELF3; IRF6; NEUROD1; MYBL1; PLAGL1; SOX10; HMGN3; THAP11; NCOA2; JUNB; CITED2; ESR1; LITAF; JUP; EGR1; RUNX3; TRIM29; NKX3-1; EHF; GATA6; ZBED2; CRYM; ZIC1; EGR3; HOXC6
Down-regulation 36 YEATS4; SOX11; SALL1; MED1; LOXL2; PBX1; ETV5; ARID4B; MED13; ZNF551; IL16; ARID1A; ZFP36L1; TRIM22; ZNF83; MEIS2; BRD2; AEBP1; SMAD1; TAL1; ZNF331; LEF1; FOXG1; TCF4; ID4; KAT6B; IRF4; ZHX2; TRIP6; CREB1; SATB1; ID1; TLE4; ETV1; ZNF586; E2F2