Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16047 Linsitinib GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 20 PPARG; TSC22D3; HSF1; SMAD3; TGFB1I1; JUP; KLF5; ERBB2; KLF11; RUNX1; ZBTB16; ZNF423; PBX1; FOXF2; FLNA; TRIM29; ZIC1; BASP1; ID1; ZNF91
Down-regulation 19 ECD; ZNF107; LEF1; FOXG1; ILF2; EYA2; ASCL1; DACH1; SATB2; SSX1; NKX3-1; TCF4; EGR3; HMGN3; EMX2; SATB1; EGR2; GATA2; ZNF586