Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16043 Ruxolitinib GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 23 FOXO3; TBX2; RNF14; PURA; SIM2; ZNF7; SUB1; NR1D2; SMAD5; TEAD1; PTTG1; ESRRG; HOXC6; SATB1; KLF10; BHLHE40; ZNF165; ZBTB38; TSC22D1; AHR; YWHAB; NR2F2; CREB1
Down-regulation 54 POU5F1B; GLI2; DLX5; FLI1; TCF12; HDAC9; ILF2; MEIS2; HOXD1; PBX1; ARNT2; PLAGL1; ST18; ZNF512B; ZEB1; ZFP36L2; TCF4; ZNF580; PBXIP1; FOXA2; ZHX2; BACH2; KLF4; ZNF24; LIN28A; SOX17; NANOG; TFAP2C; SOX2; APEX1; ERBB4; TLE4; ZBTB20; IL16; IRF8; JUN; KLF13; FOXG1; ZNF423; MNDA; ZIC1; TRPS1; PEG3; TAL1; AEBP1; ESR1; TRIB3; TWIST1; PBX3; HOXB2; NFATC4; E2F2; GATA2; ZNF586