Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16040 Alpelisib GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 11 XBP1; LEF1; REPIN1; SIAH2; FOSB; MAGED1; MYB; RFX5; TSC22D1; NR2F6; CREB1
Down-regulation 18 HDAC9; ZNF415; KLF13; NCOA2; BCL3; HOXB5; SPIB; SMAD7; GATA6; WT1; HMGN3; ZBED2; TOX; SATB1; MEIS1; ZIC1; SPDEF; KDM5D