Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16039 Alpelisib GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 35 MYBL2; FOXO4; ATF3; MEOX1; PBX1; MLXIPL; ZNF165; ZFHX4; PNRC1; TULP4; NR1H3; POU2AF1; TCF15; ZMIZ1; BBX; FOXG1; MYCN; KLF9; NCOA2; WWP1; TWIST1; FOXC1; MAF; NANOG; NR0B1; TBX3; WT1; ZSCAN18; MAFB; SNAI2; TOX; BHLHE41; ZNF91; SOX9; SATB1
Down-regulation 26 EDF1; ZNF124; HOXA11; ELF3; NR2C1; ZNF593; TRIM32; TRIM25; ESR1; NFE2L3; ERBB4; ZNF140; BCL3; NKX3-1; TRIM28; DLX5; ZEB1; SOX17; MNDA; EMX2; ELK3; MECOM; CREB1; MSX1; ID2; BASP1