Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16038 Alpelisib GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 12 KDM5A; GATA3; BBX; HTATIP2; KLF6; ERBB4; IRX5; AHR; LMCD1; ATF3; ZBTB38; CREB1
Down-regulation 31 POU2AF1; HDAC9; IRF2; MEIS2; LEF1; ZFP36L1; SHOX2; DLX5; TCF12; EYA2; BNC2; PBX1; ARID1A; IFI16; LOXL2; RUNX3; WT1; INSR; MYRF; SOX17; AEBP1; NR2F1; MNDA; ID4; DACH1; HEY1; TFAP2C; ZIC1; SPDEF; SATB1; E2F2