Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16037	Alpelisib	GSE70138	MCF10A	Human	24h	1.11uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	52	NCOA3; EED; TBX2; YEATS2; RNF111; NR4A1; MEN1; HOXD1; EYA1; SMARCC2; THAP7; SMAD6; CTBP2; PLAGL1; NR4A2; CREBZF; MYCL; DAXX; BRD4; TCF21; WT1; HIRA; IRF9; CITED2; SIX2; TWIST1; SSBP3; BNC2; MXD4; FOXC1; TLE4; FOSB; KLF7; ZBTB20; BCL6; IFI16; ZBTB16; ZNF331; CUX1; NPAS2; NR2F2; IRF6; ZNF91; ARNT2; RXRA; TRIB3; KLF4; ID3; ARID5B; FOS; SNAI2; CREB1
Down-regulation	34	EDF1; SUB1; PEG3; IRX5; NUP62; ZNF415; ZNF302; SMARCE1; RNF141; MSX1; CBX3; CRY1; CHD7; RBBP8; BHLHE40; RBPMS; MED1; NKX2-2; SMARCA1; TAF10; BMI1; TRIM16; CCNC; RUNX1; HES1; DNMT3B; ZNF83; TBX3; KLF10; PBX1; SMARCA2; SAP30; BASP1; SATB1