Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16035 Alpelisib GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 51 DMTF1; TSC22D3; CALCOCO1; NCOA3; E2F2; CREBL2; PNRC1; NR1H2; ZNF467; ZFHX3; FOSB; ZNF131; KAT2B; KLF11; STAT6; TRIM22; RORA; HOXD1; MXI1; WNT4; TDP2; FOXN3; BTG1; ERBB2; AR; BNC2; ZBTB20; PBX1; SALL2; PAWR; HMGB3; KLF4; WT1; ZBTB16; MYB; FOXA1; MYCL; PBX3; TULP3; CITED2; AEBP1; KLF2; ZNF423; ZHX2; SPDEF; NKX3-1; ZSCAN18; ID3; BASP1; NFATC4; CREB1
Down-regulation 38 RUVBL1; TLE1; MYBL2; GABPB1; MTA1; RBM14; SUV39H1; STAT5B; EGR1; ERF; MED1; SLC2A4RG; ARID4B; RUVBL2; ENO1; HMGA1; GTF2I; CBX6; FOXG1; NR2F1; FOSL1; STAT3; PITX1; BHLHE40; MYRF; BMI1; FOXC1; THAP11; PAX6; MSX1; HEY1; TGFB1; ID1; ETV1; MECOM; SATB1; CRK; SOX9