Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16033 Nvp-bez235 GSE70138 MCF10A Human 24h 0.12uM EID0004
Types Number Response transcription factors
Up-regulation 167 MYBL2; TSC22D3; CALCOCO1; FHL2; NCOA3; TGFB1I1; CREBL2; ZNF611; SOX4; PNRC1; HBP1; ZBED1; ELF3; ZNF33B; CARF; HMGA2; HMBOX1; ELF4; TOX3; ZNF93; ZNF500; ZNF160; CTBP2; ZNF358; SOX3; ZNF467; SCAI; ZKSCAN4; KDM4C; ZSCAN16; ZKSCAN1; EP300; KDM5A; ZNF224; MNT; HINFP; L3MBTL1; PBXIP1; REL; CBFA2T2; HMGA1; MED12; ZNF430; CDK7; ERBB2; CERS4; PHF20; ZNF44; KLF7; INSM1; IRF5; ZNF573; LZTR1; ZNF257; ZNF536; ZNF354A; ZMYND8; ZNF667; ZNF345; IRF9; HDAC5; ZNF117; ZBTB44; CSDC2; BAZ2B; JUP; KLF6; ID4; MED14; TBX1; EZH1; NFKB2; AFF2; ZNF426; CERS6; ZNF606; WNT4; CIR1; HOXD1; NR4A3; PAWR; ZNF91; BCL11A; NAB2; PFDN5; PRDM2; TCF25; ING4; MEF2D; NR1I2; PBX1; HTATIP2; SOX10; NKX2-1; TCF7L2; NPAS2; DDX17; DAXX; IRF6; TSG101; ZBTB16; STAT6; INSR; OVOL2; GRHL2; ZNF623; SALL2; ZNF264; ELF5; JAK2; GTF2IRD1; TULP3; ZNF217; LMCD1; NANOG; ST18; HHEX; ZNF268; KAT2B; ZNF189; MYCL; FOXE1; HOXB13; GATA6; MAFF; TCF7; KLF4; TCEB2; MXD4; AES; ERBB4; BHLHE41; IRF8; EYA1; THAP10; FOSB; CHD9; HOXB2; ZNF165; SATB2; ZSCAN18; CBFA2T3; MED13; TSC22D1; PPARGC1A; ZBTB20; ATF3; MAF; ZBED2; AR; BCL6; MYB; FOS; DACH1; TRIM29; AEBP1; RELB; TFAP2C; PBX3; OLIG2; SOX9; FLNA; EHF; SOX11; ZHX2; CREB1; KDM5D
Down-regulation 70 CCNA2; MYCBP; GTF2A2; PARP1; EED; EZH2; RUVBL1; GMNN; NUP62; TCERG1; YEATS4; NFIL3; HMGB1; SUB1; RUVBL2; CENPF; HLTF; TBP; TFAM; MED4; ZNF473; BMI1; PRKDC; SUV39H1; HSF2; WDHD1; WDR77; HMGB2; CCNE1; MSX1; TAF5; ZMYND11; BATF3; ITGB3BP; TAF1A; MECOM; RBM14; XRCC6; BRCA1; HOXA1; LEF1; ING3; PTTG1; TFDP1; MED1; HOXB7; SMAD5; SAP30; ENY2; XBP1; CTR9; BCLAF1; C1QBP; PSIP1; PMS1; DBP; ZNF22; TRIM28; CALR; TCEA2; ID1; SMAD1; MAFB; FOSL1; ID3; YWHAB; ID2; CDK2; ZBTB18; IKZF1