Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16032 Nvp-bez235 GSE70138 MCF10A Human 24h 0.37uM EID0004
Types Number Response transcription factors
Up-regulation 94 TSC22D3; SUV39H1; FHL2; SOX2; SOX4; NCOA3; HBP1; PHF20; HDAC9; HMGA2; HOXD1; DPF2; ELF3; ELF4; TAF7; TGFB1I1; MAFF; BTG1; BTF3; ZNF160; MED12; MNT; ZNF358; ZNF536; FOXD1; KLF6; ERBB2; CDK7; ZBTB16; HIVEP2; ZNF611; ZBED1; LITAF; BRD4; ZNF33B; BANP; EP300; ZKSCAN1; BAZ2B; ZNF721; MXD4; FOSL2; KLF7; PNRC1; ZNF281; ZBTB43; BCL10; NRIP1; RARA; TCF25; TSG101; HIVEP1; NFKB2; EYA1; EGR1; SRCAP; APEX1; PSPC1; LMCD1; FOXO3; SERTAD2; HLF; IRF7; AES; REPIN1; ATF4; BCL3; NFIC; INSM1; AHR; HTATIP2; SNAI2; REL; FOXN3; SP100; KLF5; SIX2; TOX3; CHD9; PDLIM1; HEY1; TBL1X; KDM5B; CUX1; IRF9; TRIM29; ZBTB38; FLNA; BCL11A; CRYM; ELK3; ZIC1; ZNF91; CRK
Down-regulation 100 MYBL2; CCNA2; MYCBP; PARP1; EZH2; RUVBL1; FOXM1; GMNN; TCERG1; EED; DNMT1; GTF2A2; ZNF107; CHAF1B; RNF138; WDHD1; HMGB1; HDAC1; TFAM; POU2AF1; TTF2; ATF5; TGS1; WDR77; NOC2L; SNIP1; BAZ1B; BLM; TOPORS; PSMC3IP; PA2G4; ZNF232; HMGB2; HLTF; HSF2; TAF5; NANOG; BRCA1; ITGB3BP; RBBP8; PRKDC; WT1; SUB1; RBM14; SUZ12; CCDC59; ZNF273; ILF2; LEF1; STAT1; GATAD2A; CERS6; PSMC3; RUVBL2; ZNF266; FOXF1; CDK2; TCF21; ZNF180; NUP62; ZNF331; PTTG1; E2F8; RERE; CRY1; JUN; SSRP1; HES1; TFDP1; ISL1; PBX1; C1QBP; DNMT3B; ING2; MYBL1; CEBPG; HIRA; BCL11B; HHEX; CHD1; ID2; HMGB3; HNRNPD; MEIS2; KLF4; CCNC; RFX5; MTF2; MNDA; NFE2L3; PBX3; MAFB; FOSL1; ID1; AEBP1; SAP30; TFAP2C; SOX11; E2F2; GATA2