Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16031 Nvp-bez235 GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 84 TSC22D3; SOX4; TGFB1I1; FHL2; TSG101; SSBP2; MAFG; DMTF1; HOXD1; PHF20; MNT; HTATIP2; IRF7; HBP1; ZNF358; ELF4; PPP1R13L; KLF7; ELF3; HMGA2; HDAC9; MED12; SP100; CDK7; HIVEP2; KLF6; NFE2L1; SMAD2; MAFF; YEATS2; BPTF; BCL10; SRCAP; JUP; ZNF224; ERBB2; PHF1; KLF5; SP110; ZNF611; STAT6; HDAC5; ATF4; SUPT3H; ZBTB43; PLAG1; RCOR3; UBE2B; ZNF536; ZNF264; ZNF44; JUND; FOXO3; REL; NAB2; ZNF117; CREB3; BTG1; ZMYND8; ZNF160; PDLIM1; MXD4; TCEA1; ZNF91; AHR; ATF3; ERG; SNAI2; LITAF; TCF3; INSR; EGR1; IRF9; NPAS2; IFI16; SMARCA1; FOS; TP63; BHLHE41; FOSB; RELB; TRIM29; SOX9; CREB1
Down-regulation 92 CCNA2; MYBL2; MYCBP; EZH2; PARP1; FOXM1; GMNN; GTF2A2; XRCC6; SUB1; RUVBL1; HMGB1; EED; NOC2L; SUV39H1; WDR77; DNMT1; NFIL3; HMGB2; NRIP1; ILF2; BCLAF1; BAZ1B; GABPB1; TFAM; PA2G4; TFDP1; HSF2; ADRB2; YEATS4; UBE2L3; CENPB; CRY1; BLM; CCDC59; ECD; RBM14; RNF138; TAF9; RBL1; HLTF; LEF1; NUP62; BRCA1; PTTG1; HOXB7; TAF9B; MSX1; STAT1; PREB; ZNF200; RNF6; ZNF267; SALL1; C1QBP; RBBP8; HOXA10; RBBP7; CEBPZ; HEY2; ASCL1; CCNC; SMAD5; FUBP1; ITGB3BP; HMGB3; TEAD4; BAZ1A; SFPQ; SIAH2; TRIM28; BMI1; CDK2; RUVBL2; NANOG; TBX3; ESR1; CBFB; ZNF331; RFX5; FOSL1; HOXB6; SMAD1; MAFB; HEY1; NKX2-2; ID1; ETV1; ID2; CRYM; HOXC6; GATA2