Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16030 Nvp-bez235 GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 168 TGFB1I1; TSC22D3; PNRC1; NCOA3; CALCOCO1; HBP1; PBXIP1; ZNF33B; MED12; HDAC5; ZNF500; ZNF688; BCL10; ZNF573; CIR1; ZKSCAN1; ZNF654; RSF1; GTF2F1; ZNF611; ZNF358; ST18; ZNF354A; ELF4; ZNF768; VDR; STAT6; ZNF623; IRF9; HMGA1; EP300; CARF; TRIP11; JUP; RING1; YEATS2; SOX12; MAFG; AEBP1; TCF7; ZNF345; MED15; SRCAP; SCAI; ZNF224; REL; ZNF112; ZNF529; HMBOX1; TEAD3; FOXI1; ZNF219; PHF20; NAB2; ZBTB16; CREBL2; ZNF467; KDM5B; CBX7; IRF6; ARID3A; ZNF117; NFKB2; OVOL2; ZNF136; ZNF350; ZNF155; ERBB2; HOXD1; ARL2BP; HIC2; ZFHX3; MNT; EZH1; GRHL2; NKX2-1; PHF1; HSF1; ZNF415; HTATIP2; HIVEP1; PRDM2; ZNF44; SOX4; TFCP2; BRWD1; AES; ZNF268; FOXO3; ZNF264; BTG1; ZNF93; ZNF141; ZNF665; KLF11; IRF7; SIM1; WNT4; TSG101; ZNF536; TDP2; KLF7; SUPT3H; TRIM22; DLX5; ZNF32; CIZ1; ING4; ARNT2; TWIST1; ZNF160; ZNF91; JUND; ZMYND8; ZNF394; EGR1; SOX17; NFIC; MAFF; SNAI2; SALL2; RUNX1; TFAP2C; ERBB4; FOXF2; ZNF281; INSR; DLX2; LMCD1; HHEX; CBFA2T3; TCF7L2; NCOA2; SP100; ZNF43; HIRA; SSBP3; BCL11A; TCF3; ATF3; ZSCAN18; KLF13; TULP3; CUX1; TAL1; TRIB3; TGFB1; NPAS2; ZNF217; TXNIP; FOS; OSR2; MAF; BACH2; CRYM; MEIS2; TBX3; ZNF423; RELB; HEY1; TSC22D1; ARID5B; FLNA; TRPS1; EMX2; KDM5D; NFATC4; E2F2
Down-regulation 89 CCNA2; MYCBP; PARP1; EZH2; MYBL2; GTF2A2; EED; ADRB2; HDAC2; RUVBL1; SUV39H1; HMGB1; SUB1; ATF6; RAN; HSF2; TCERG1; RBM14; TFAM; BAZ1B; RBL1; NUP62; ATF5; YEATS4; PREB; WHSC1; WDHD1; PURA; ENO1; BCLAF1; WDR77; UBP1; BLM; PBRM1; TP53; C1QBP; DEK; ING3; PSMC3IP; TAF5; HDAC1; HLTF; CBFB; TAF9; BRCA1; BATF3; HES1; CTR9; CCNE1; XBP1; PA2G4; ITGB3BP; PSIP1; DNAJC2; CRY1; BMI1; RBBP7; TFDP1; TRIM28; CEBPZ; HMGB2; ETS2; ZBTB18; CBX3; RUVBL2; RNF6; GTF3A; SSRP1; ZBTB38; MED1; SAP30; PEG3; NFIB; FOSL1; HMGN3; CHD7; DNMT3B; ID2; IRF4; ASCL1; HOXC10; IRX5; MAGED1; TOB1; PITX1; ETV1; HOXC6; NR2F2; SATB1