Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16029 Nvp-bez235 GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 132 TSC22D3; FHL2; TGFB1I1; ZNF688; HBP1; NFKBIA; ZNF532; MAFG; PNRC1; NCOA3; MED12; ZNF358; ELF4; BTF3; SREBF2; EP300; PHF1; HMGA2; ZNF93; KLF6; BTG1; ZNF611; RCOR3; NKX2-1; CREBL2; MNT; ERBB2; SOX4; KDM5B; MZF1; FOSB; KLF7; HINFP; ZNF771; MECP2; JUND; CALCOCO1; ZMYND8; EZH1; HOXD1; MKL1; STAT2; PPP1R13L; ZNF671; LITAF; HDAC9; TCF25; CDIP1; SUPT3H; NFIX; ZNF281; ZNF665; HDAC5; TEAD3; HIVEP2; ZBTB16; CBX7; PHF20; SP140; BAZ2B; TSG101; ZNF224; ZNF160; SP110; LOXL2; PBXIP1; ZSCAN18; MTA1; CSDC2; KLF3; ZNF586; TLE2; FOXN3; RARA; ZNF426; NFIC; ETV1; MAFF; ZMIZ1; PRRX2; HMBOX1; ZNF91; NCOA4; ZNF721; EGR1; MXD4; ZNF264; PRRX1; KLF11; TXNIP; PEX2; ZNF3; IRF7; FOXI1; CSDE1; ID3; SRCAP; NCOR2; NAB2; ZNF83; CHD9; ATF3; MXI1; PDLIM1; TWIST1; NRIP1; PEG3; GATA2; IL16; ZFPM2; RELB; ZNF117; LMCD1; CTBP2; DDX5; RXRA; TCF7L1; BACH1; ZEB1; KLF2; VDR; SMAD7; FOXO1; SNAI2; GATA6; ID4; TSC22D1; FLNA; OLIG2; ESR1; BASP1; EGR2
Down-regulation 86 CCNA2; MYBL2; MYCBP; GTF2A2; GMNN; PARP1; TCERG1; RUVBL1; EZH2; FOXM1; EED; YEATS4; HLTF; PSMC3IP; SUV39H1; SUB1; RUVBL2; NFIL3; HMGB1; TFAM; DNMT1; ADRB2; ZNF107; BRCA1; WDHD1; PA2G4; PREB; HMG20B; RBM14; RNF138; RBBP8; HOXA1; HDAC1; DNAJC2; ZNF146; ACTL6A; CEBPZ; CRY1; CTR9; BCLAF1; ILF2; CBX5; RAN; NEDD8; ZNF22; SHOX2; NUP62; TFDP1; BMI1; HMGB2; BLM; MYBL1; POU4F1; NR2F1; HOXC10; PMS1; PTTG1; PAX6; DNMT3B; ITGB3BP; STAT1; SSRP1; CEBPG; TRIM28; MYB; BAZ1A; MTF2; E2F8; WWTR1; HES1; HOXB7; ZIC1; POU2AF1; RREB1; SSX1; CCNE1; RFX5; ID2; TOB1; CRYM; CDK2; TRIP6; SAP30; NFIB; SATB1; E2F2