Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15990 Pf-477736 GSE70138 MCF10A Human 24h 1.11uM EID0004
Types Number Response transcription factors
Up-regulation 36 TSC22D3; NCOA3; ESRRA; NFIL3; NR1I2; NFE2L1; IRF7; BCL10; ZFP64; ASH2L; SMAD3; NFAT5; EGR1; TDP2; MNT; ATF4; TRIM22; ATF3; FOS; GATA2; HTATIP2; SIX2; THAP11; FOSB; ID3; ID1; HEY1; LITAF; ELF1; NR4A2; TRIB3; WT1; ESR1; TRIM29; SNAI2; ZNF91
Down-regulation 38 CCNA2; MYBL2; FOXM1; TRRAP; TAF9B; BAZ1B; CAMTA1; MED21; NRIP1; PSMC3IP; RBM14; GATAD2A; HMGB2; ING3; DNAJC2; SMAD1; HMGB1; CCNC; SHOX2; INSM1; TBL1XR1; RUVBL2; SUV39H1; ASCL1; HMGB3; WWTR1; ZBTB20; HMGN3; ZFP36L1; SOX11; NKX3-1; ID4; ZIC1; TRIP6; KLF4; TCF4; CREB1; HOXC6