Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15989 Pf-477736 GSE70138 MCF10A Human 24h 3.33uM EID0004
Types Number Response transcription factors
Up-regulation 93 SOX2; TSC22D3; BCL10; FOXO4; NCOA3; TRIM22; IRF7; NFKBIA; ATF4; NRBF2; ZNF611; BTG1; RBBP5; MED12; TERF1; HDAC4; SPI1; PHF20; ZNF224; SIRT2; CALCOCO1; PBXIP1; CIR1; TP63; ADNP; PNRC1; ZNF160; STAT2; TSG101; HBP1; CTNNB1; TSC22D4; CBX7; TBL1X; EGR1; ZNF721; JUP; XBP1; PBX2; THAP11; SP2; NAB2; ZBTB7A; RARA; CTR9; LITAF; ZNF652; MAF; TBL1XR1; ZBTB16; TCF15; ZNF587; BBX; SRCAP; IRF9; BCL3; NCOA2; KLF10; MED13; TRIB3; MAFF; TRIM16; ID4; ZNF195; VDR; JUNB; TOX3; HOXD1; TAF10; FOXO1; FOXA1; FOS; NR0B1; DDIT3; FOXG1; NR4A2; PBX1; EGR2; MXI1; SCAND1; JARID2; IRF1; NKX3-1; ID3; SPDEF; TRPS1; ATF3; ID1; MYRF; TOB1; SOX9; FLNA; BHLHE41
Down-regulation 67 CCNA2; FOXM1; MYBL2; HMGB2; ADRB2; PARP1; GMNN; NPM1; WHSC1; EZH2; NEUROD1; PTTG1; HSF2; GTF3A; CAMTA1; HMGB1; CHD7; RNF138; HNRNPD; INSM1; SFMBT1; SETD2; RBM14; COPS2; CENPF; KLF4; NUP62; CRY1; PURA; RBL2; RBPMS; PHOX2B; YBX1; EN1; RAN; BRCA1; RBBP8; TGFB1I1; ESRRG; NHLH2; MBD2; MYT1L; PAX5; BRIP1; SOX11; SUB1; ZNF32; CCNC; HMGN3; SHOX2; ZIC1; SUV39H1; CBFB; FUBP1; EMX2; ZNF22; GTF2I; HIRA; SAP30; PAX6; JUN; TSC22D2; ISL1; NR2F2; MSX1; GATA6; ELK3