Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15988 Pf-477736 GSE70138 MCF10A Human 24h 10uM EID0004
Types Number Response transcription factors
Up-regulation 41 TSC22D3; PNRC1; ATF3; TRIM22; EGR1; IRF7; HDAC6; HTATIP2; NFIL3; CALCOCO1; HBP1; HOXD1; TSG101; ZSCAN31; RFX5; ZBED2; FOSB; JUP; MXD4; BTG1; TAF10; WNT4; STAT1; TRIM29; SCAND1; NR4A2; IRF9; INSM1; BRD2; JUN; ZNF331; ZNF165; SMARCA1; EHF; VPS72; TFAP2C; MYRF; ID2; ASCL1; GATA6; SATB1
Down-regulation 34 CCNA2; MYBL2; ADRB2; EZH2; PARP1; HMGA2; RBL1; FOXM1; ZNF200; HMGB1; HNRNPD; NRIP1; ZEB1; TLE1; SALL1; PRKDC; LEF1; RBM14; MLXIP; PURA; HDAC9; TULP4; BRCA1; MYB; ING2; SMAD1; DLX5; HMGB2; SATB2; FOXG1; FOSL1; VGLL4; EMX2; CREB1