Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID15982 Roscovitine GSE70138 MCF10A Human 24h 0.04uM EID0004
Types Number Response transcription factors
Up-regulation 57 NR3C1; STAT5B; FOXO4; ZNF646; MLXIPL; MEIS2; ATF3; CIC; RBFOX2; ZNF711; HOXA10; MYBL1; FOXD1; HMX1; MYOG; POU2AF1; TCF15; ZEB1; SIM1; ALX1; IRF1; MAZ; SPIB; BTG1; BCL3; PITX1; ID1; NR4A1; HIC2; FOXF2; EYA1; FOXF1; SOX13; JUNB; SIX2; ID3; RXRA; TRPS1; FOSB; SMAD1; ZNF423; TWIST1; GATA2; NR2F1; MEIS1; BASP1; ZEB2; JUP; HOXB2; VPS72; TFAP2C; ZBTB18; HEY1; SOX9; ZNF91; SATB1; CREB1
Down-regulation 27 PUF60; ZBTB16; MAFG; SIM2; E2F3; HDAC1; SMARCE1; HTATIP2; CREG1; MAFB; ZBTB1; MAGED1; ENY2; NPAS2; ESR1; FOXO1; PIR; ERBB4; YWHAB; TXNIP; KLF11; HOXC6; LMCD1; MYT1L; FOS; KDM5D; BHLHE41