Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID15981	Roscovitine	GSE70138	MCF10A	Human	24h	0.37uM	EID0004

Response Information :

Types	Number	Response transcription factors
Up-regulation	39	NCOA3; ZNF589; NR1D2; BCL11B; RNF138; SMAD2; NR3C2; BBX; ETS2; BHLHE40; ING2; PLAGL1; ZBTB38; DACH1; POU4F1; CREM; HOXD1; KLF10; ZNF423; HMGB3; HHEX; TOX; HMGB2; KLF5; SMAD7; ERG; WT1; ZFP36L1; BRD2; PEG3; MYT1L; KDM5D; PAX5; SNAI2; TLE4; HOXC6; BASP1; CREB1; SATB1
Down-regulation	44	GTF2F1; ETV4; KAT2A; PSMC3; ETV5; STAT2; ATF5; AIP; NFKB2; ELF5; ILF2; SIX2; AEBP1; NFE2L3; NKX2-1; PRRX1; MNDA; NR1H2; GTF3A; MED13; NCOR2; SHOX2; CITED1; SOX13; MYRF; DLX5; ZBTB16; MYBL1; PBX3; TXNIP; NR2F6; FOXF2; FLNA; TFAP2C; ASCL1; CALR; MEIS2; ARNT2; TWIST1; OLIG2; NR2F1; BHLHE41; GATA2; ETV1